GenScript Molecular Biology Services
GenScript provides one expert source for reliable and economical molecular biology outsourcing. With vast experience in gene synthesis, custom cloning, vector design and construction, mutagenesis, ORF cloning and both small- and large-scale plasmid preparation, GenScript's molecular biology team can take on any technical challenge to promote the client's research and experimentation.
| Gene Synthesis |
| GenScript's proprietary gene synthesis technology produces custom genes de novo using only customer's gene or protein sequence. Delivery is guaranteed. As one of pioneer companies of the gene synthesis service industry, GenScript has synthesized tens of thousands of genes for customers around the world. Over the years, GenScript has fine-tuned a variety of unique technology platforms, including advanced gene design tools and methods for the synthesis of GC-rich and extremely long genes. |
| DNA Constructs |
| Outsourcing DNA construct preparation to GenScript can free researchers' talents from the wearing burden of tedious work, improving productivity. GenScript offers a full spectrum of DNA construct production services. Our construct department has the capacity and the expertise to produce tailored, ready-to-use DNA constructs for any application. Our vast experience and large-scale oligo synthesis and DNA sequencing facilities allow us to offer excellent services at very competitive prices. |
| Mutagenesis and PCR |
| Mutagenesis and PCR cloning are routine techniques common in molecular biology laboratories. These tasks are required so often that they tend to become a challenge to the lab scientists' patience and attention. GenScript offers mutagenesis and PCR cloning services as a complement to its gene synthesis service, relieving lab scientists of such tedious and tiresome activities. Although GenScript gene synthesis is reliable and versatile, simple PCR cloning, subcloning, or mutagenesis may be more cost-effective than de novo gene synthesis for some projects. |
| Plasmid Preparation |
| GenScript plasmid preparation services provide ultra-pure plasmid DNA, both individual constructs for research labs and large quantities for biotech suppliers and pharmaceutical companies. For biotech suppliers, we provide complete vector plasmid manufacturing services. Our services include industry-scale plasmid production, batch tube aliquoting, labeling, packaging, and step-by-step total QC management. These cost-effective plasmids are provided ready-to-market. |
| ORF Cloning |
| The GenScript GenPoolTM of open reading frame (ORF) clones contains 610, 283 ORFs from 53 species, and the number is growing. Each ORF is cloned into the pDream2.1 vector, which allows for expression in bacteria, Sf9 cells, and mammalian cells. Our customers may select any gene from the GenPoolTM. Delivery is guarantee. |
| Large-Scale Sequencing |
| GenScript offers quick, high-quality, cost-effective DNA sequencing services. Our direct DNA sequencing service uses state-of-the-art equipment, including the ABI 3730xl DNA Analyzer. This flexible and easily customized system is applicable to PCR amplicons, low-copy plasmids, and high-copy plasmids. Our sequencing service is compatible with studies involving mutations, polymorphisms, screening, construct generation, genome sequencing, and the cloning of new genes. |
| Synthetic Gene Variant Library |
| Synthetic libraries constructed using the in vitro molecular optimization method provide one useful approach to the systematic study of protein properties, regulation, and function. GenScript's strong expertise in de novo gene synthesis allows us to synthesize complex protein libraries without any dramatic increase in cost. Our synthetic library services include site-directed mutagenesis libraries, sequential permutation scanning libraries, and randomized and degenerated libraries. |
| Shotgun Library |
| GenScript provides high-quality shotgun library construction and sequencing services from a variety of sources and formats including BAC, PAC, Cosmid, and Fosmid. Clones within the shotgun libraries can be tailored to carry inserts within a narrow size range. Our final delivery includes transformed cells or frozen subclones arrayed on 96-well plates, ready to prep and sequence. |
| Knock-Out Vector Construction |
| GenScript's advanced molecular biology platform has provided more than 160 targeting vectors to customers worldwide. These targeting vectors have been successfully used in traditional and conditional knock-out, knock-in, and many other genetic modification projects. |
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