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*This product has been discontinued! *
| Product Name |
Human OX1 Receptor Membrane Preparation |
Species |
Human |
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Description |
The orexin/hypocretin peptides orexin A and orexin B (also known as hcrt-1 and hcrt-2) are 33- and 28-amino acid peptides, respectively. They are preferentially expressed in hypothalamus. The orexins have a range of physiological functions including feeding control, energy metabolism, neuroendocrine function modulation, and sleep-wake cycle regulation. The two orexin receptor subtypes OX1 and OX2 both mediate the action of orexin-A and orexin-B and couple efficiently through Gq/11 to activate phospholipase C and lead to elevation of intracellular calcium. |
Host Cell |
CHO-K1/OX1 (Cat. No. M00224) |
Concentration |
1 mg/ml in 50 mM HEPES, 5 mM MgCl2, 1 mM CaCl2 and 0.2% BSA, pH7.4 |
Storage |
Store at -80°C |
Application |
Binding assay for OX1 receptor |
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TECHNICAL MANUAL: 11332_20091127004322.PDF (PDF)