CHO-K1/AMY1/Gα15 Stable Cell Line

*This product has been discontinued!*

Amylin receptors have always been closely associated with calcitonin (CT) receptor. This can be explained because amylin receptors are multimeric complexes, formed by CT receptor interaction with RAMPs. The CT receptor interacts with the three RAMPs, generating multiple subtypes of amylin receptor (AMY1-3). The AMY1 receptor is a heterodimeric complex of the CT receptor and RAMP1. GenScript's AMY1-expressing stable cell line was made in CHO-K1/Gα15 host cell and optimized for calcium assays.

Cat. No.	M00475
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Product Introduction Culture Conditions

Description

Amylin receptors have always been closely associated with calcitonin (CT) receptor. This can be explained because amylin receptors are multimeric complexes, formed by CT receptor interaction with RAMPs. The CT receptor interacts with the three RAMPs, generating multiple subtypes of amylin receptor (AMY1-3).
The AMY1 receptor is a heterodimeric complex of the CT receptor and RAMP1. GenScript's AMY1-expressing stable cell line was made in CHO-K1/Gα15 host cell and optimized for calcium assays.

Synonyms

Human Recombinant Amylin Receptor AMY1 Stable Cell Line

Product Introduction

Storage

Liquid nitrogen immediately upon delivery

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Culture Conditions

Culture Medium	Ham's F12, 10% FBS
Freeze Medium-DATA	45% culture medium, 45% FBS, 10% DMSO

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Citations

1. Tomabechi Y, et al. Glycosylation of Pramlintide: Synthetic Glycopeptides that Display In Vitro and In Vivo Activities as Amylin Receptor Agonists. Chemistry. (2013-10)