 Mutagenesis Services
Mutagenesis is central to molecular biology, facilitating research in a variety of fields, including studies of gene regulatory elements, DNA-protein interaction, protein structure/function, enzyme active sites, and novel proteins. GenScript's mutagenesis services, powered by sophisticated gene synthesis technology and high performance GS polymerase, include point mutations, deletions, and insertions. They can be customized to fit any scientific applications.
- Sequence confirmation: The sequence of template DNA will be confirmed by sequencing upon request.
- Primer Design/Synthesis: Primer design and synthesis for mutagenesis are included.
- Mutation Introduction: Mutations are introduced by PCR.
- Mutant Screening: Every mutation is verified by sequencing.
- Mutant DNA Preparation: GenScript can manufacture mutant DNA plasmid up to 1000 mg scale with required purity and endotoxin levels.
Competitive Advantages:
- Unparalleled Accuracy: GenScript's high performance GS polymerase ensures accuracy of mutants, avoiding creation of unwanted mutations.
- Unlimited Sites: Using our sophisticated mutagenesis technology, GenScript can introduce mutations at any site.
- Mutation on Large Construct: Our technology is optimized to introduce mutations, insertions, and deletions on constructs as large as up to 8 kb (including target gene and its vector).
- Comprehensive Service Package: We offer comprehensive upstream and downstream services, including template sequencing, expression vector construction, and protein expression and purification
- Most Competitive Prices: Our services are at least 50% less expensive than those of our competitors.
Pricing:
| Cat. No. |
Price per mutagenesis |
| SC1023 |
Starting at $295.00 |
* The list price is only for genes less than 1 kb in length.
* For genes longer than 1 kb, an additional $100 per kb will be applied.
* One mutation is defined as any combination of mutations within a 10-base frame.
Sample Submission Requirements:
Please provide following:
- The complete sequence of the template including the target gene and its vector
- Mutation specifications
- A sufficient amount of culture if the starting material is bacterial culture
- Maps and antibiotic resistance of the template and destination vectors
- A 2 µg template DNA if the starting material is DNA
Delivery Specifications
Our typical turnaround is about 10 business days. Our delivery package includes:
- 4 μg lyophilized destination vector containing the gene
- Sequence chromatograms covering your gene (electronic)
- Construct map for the plasmid (electronic)
- Quality assurance certificate
 Quotations and Ordering:
 For quotation requests and questions, you may contact us by phone, email, fax, or via our online quotation system.
Orders can be placed by phone, email, fax, or online with a formal PO (Purchase Order) or credit card.
Please send your samples with full shipping information and PO number (if applicable) with a hard copy of the completed Mutagenesis Quotation Request Form to Mutagenesis Services, GenScript USA Inc., 120 Centennial Ave., Piscataway, NJ 08854, U.S.
Our customer service representatives are available 24 hours Monday through Friday.
You may contact us anytime for assistance.
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