|
A
B
C
D
E
F
G
H
I
J
K
L
M
N
O
P
Q
R
S
T
U
V
W
X
Y
Z
Hot Products
*For Non-Clinical Research Use Only*
|
Prepro Thyrotropin-Releasing Hormone (TRH) (178-199)  |
|
|
| Full Name |
Prepro Thyrotropin-Releasing Hormone (TRH) (178-199) |
| Alias |
TRH (178-199) |
|
Sequence
(one-letter code) |
FIDPELQRSWEEKEGEGVLMPE |
Sequence
(three-letter code) |
{PHE}{ILE}{ASP}{PRO}{GLU}{LEU}{GLN}{ARG}{SER}{TRP}{GLU}{GLU}{LYS}{GLU}{GLY}{GLU}{GLY}{VAL}{LEU}{MET}{PRO}{GLU} |
| Description |
Prepro-TRH 178-199, a peptide with corticotropin release inhibiting activity at the pituitary, on the Porsolt forced swim test (FST) of depressive behavior in rats. Prepro TRH (178-199) derived from prepro-TRH inhibits basal and CRF-stimulated ACTH synthesis and secretion. Biological activity of this peptide resides in the C-terminal fragment as prepro-TRH 178-199 and prepro-TRH 191-199 were equally potent in the FST. These data suggest that endogenous prepro-TRH 178-199 with its antidepressant-like activity might contribute to the etiology or manifestation of depressive behavior.
|
| Solubility |
Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents. |
| Purity |
> 95% |
| Storage |
Before using, store the peptide in the DRY form at 0 - 5°C. For best and repeatable results, rehydrate the peptide immediately before using. Do not re-freeze any unused portions. |
| Notes |
|
Related Products
 |
1 |
Peptide Services: GenScript's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.
|
2 |
Standard Peptide Synthesis: GenScript offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. GenScript FlexPeptideTM technology can synthesize peptide as long as 200 amino acids, a world record for such technology.
|
3 |
Peptide Modifications: GenScript offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.
|
4 |
Peptide Libraries: GenScript has developed a rapid high-throughput parallel peptide synthesis platform, providing custom libraries of unbound peptides of 5-20 mer at very competitive prices.
|
|
Document-HPLC: 1954_20060721145613.PDF (PDF)