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Thyrotropin-Releasing Hormone (TRH)

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Thyrotropin-releasing hormone (TRH) is a tripeptide hormone secreted by the hypothalamus that stimulates the release of thyrotropin. This tripeptide is involved in the regulation of the hypothalamic pituitary-thyroid axis; it stimulates the synthesis and release from the anterior pituitary of thyrotropin (TSH) and prolactin.
RP10112
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Overview
Synonyms L-Pyroglutamyl-L-histidyl-L-prolinamideThyroliberin
Description Thyrotropin-releasing hormone (TRH) is a tripeptide hormone secreted by the hypothalamus that stimulates the release of thyrotropin. This tripeptide is involved in the regulation of the hypothalamic pituitary-thyroid axis; it stimulates the synthesis and release from the anterior pituitary of thyrotropin (TSH) and prolactin.
Cas No 24305-27-9
Sequence
{pGLU}{HIS}{PRO}-NH2
Sequence Shortening pEHP-NH2
Molecular Formula C16H22N6O4
C Terminal NH2
Molecular Weight 362.38
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Properties
Purity > 95%
Solubility The peptide is soluble in water to 10 mg/ml, appearing clear and colorless.
Form Lyophilized
Storage Store the peptide at -20°C. Keep container tightly closed.
Note TRH and phorbol esters stimulate sphingomyelin synthesis in GH3 pituitary cells.
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