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*For Non-Clinical Research Use Only*
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Calcineurin Autoinhibitory Peptide  |
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| Full Name |
Calcineurin Autoinhibitory Peptide |
Sequence
(one-letter code) |
ITSFEEAKGLDRINERMPPRRDAMP |
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Sequence
(three-letter code) |
{ILE}{THR}{SER}{PHE}{GLU}{GLU}{ALA}{LYS}{GLY}{LEU}{ASP}{ARG}{ILE}{ASN}{GLU}{ARG}{MET}{PRO}{PRO}{ARG}{ARG}{ASP}{ALA}{MET}{PRO} |
| Description |
Corresponds to a C-terminal domain (residues 457-482) of the calmodulin-binding domain of calcineurin. Specific calcineurin inhibitor. Does not inhibit CaM kinase II, protein phosphatase I or 2A. Inhibits Mn2+-stimulated calcineurin activity (IC50 = 10 mM using 32P myosin light chain as a substrate) but has no effect on Ni2+-stimulated activity. |
| Solubility |
H2O |
| Purity |
> 95% |
| Storage |
Store at -20°C. Keep tightly closed. Store in a cool dry place. Aqueous stock solutions are stable for up to 2 months at -20°C. |
| Notes |
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Related Products
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1 |
Peptide Services: GenScript's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.
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2 |
Standard Peptide Synthesis: GenScript offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. GenScript FlexPeptideTM technology can synthesize peptide as long as 200 amino acids, a world record for such technology.
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3 |
Peptide Modifications: GenScript offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.
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4 |
Peptide Libraries: GenScript has developed a rapid high-throughput parallel peptide synthesis platform, providing custom libraries of unbound peptides of 5-20 mer at very competitive prices.
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Document-MSDS: 5993_20080923205904.PDF (PDF)