PACAP (6-27), human, ovine, rat

*This product has been discontinued!*

PACAP (6-27), PACAP-27 inhibitor, is a specific inhibitor of PACAP-27 stimulated adenylate cyclase. It allows a clear functional discrimination between PACAP-27 and PACAP-38 receptors. PACAP-(6-27) diminished, in a dose-dependent manner, the increase in adrenal CA secretion induced by PACAP-27. The results also indicate that the CA response to either PACAP-27 or VIP was selectively inhibited by PACAP-(6-27) but not by VIP-(10-28). It is concluded that PAC1 receptor is primarily involved in the CA secretion induced by both PACAP-27 and VIP in the canine adrenal medulla in vivo.

Cat. No.	RP10337
Size	Buy in bulk

Ask us a question

Overview Properties

Note

For PACAP receptor studies. Inhibits PACAP27-stimulated but not PACAP38-stimulated adenylate cyclase activity

Overview

Cas No	136134-68-4
Sequence	{PHE}{THR}{ASP}{SER}{TYR}{SER}{ARG}{TYR}{ARG}{LYS}{GLN}{MET}{ALA}{VAL}{LYS}{LYS}{TYR}{LEU}{ALA}{ALA}{VAL}{LEU}-NH₂
Sequence Shortening	FTDSYSRYRKQMAVKKYLAAVL-NH₂
Molecular Formula	C₁₂₁H₁₉₃N₃₃O₃₁S₁
C Terminal	NH₂
Molecular Weight	2638.09

Back

Properties

Purity	> 95%
Solubility	Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents.
Storage	Store at -20°C.

Back