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*For Non-Clinical Research Use Only*
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Pancreatic Polypeptide, Rat  |
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|
| Full Name |
Pancreatic Polypeptide, Rat |
| Alias |
PP |
|
Sequence
(one-letter code) |
APLEPMYPGDYATHEQRAQYETQLRRYINTLTRPRY-NH2 |
Sequence
(three-letter code) |
{ALA}{PRO}{LEU}{GLU}{PRO}{MET}{TYR}{PRO}{GLY}{ASP}{TYR}{ALA}{THR}{HIS}{GLU}{GLN}{ARG}{ALA}{GLN}{TYR}{GLU}{THR}{GLN}{LEU}{ARG}{ARG}{TYR}{ILE}{ASN}{THR}{LEU}{THR}{ARG}{PRO}{ARG}{TYR}-NH2 |
| C-Terminal |
NH2 |
| Description |
Pancreatic Polypeptide is an agonist at Y4 neuropeptide Y receptors. Pancreatic polypeptide (PP) is a 36-amino-acid secretory peptide that is predominantly produced by the pancreas. The exact physiologic role of PP in healthy individuals has not been fully defined. It has been shown, however, that pancreatic polypeptide affects the secretion of pancreatic enzymes, water, and electrolytes. Its effect is biphasic in that PP initially enhances secretion and then inhibits secretion. PP increases gastric emptying and gut motility. Pancreatic polypeptide also relaxes the pyloric and ileocecocolic sphincters, the colon, and gallbladder. PP levels increase after ingestion of food and remain elevated from four to eight hours. |
| Solubility |
Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents. |
| Purity |
> 95% |
| Storage |
Store at -20°C |
| Notes |
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Related Products
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1 |
Peptide Services: GenScript's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.
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2 |
Standard Peptide Synthesis: GenScript offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. GenScript FlexPeptideTM technology can synthesize peptide as long as 200 amino acids, a world record for such technology.
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3 |
Peptide Modifications: GenScript offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.
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4 |
Peptide Libraries: GenScript has developed a rapid high-throughput parallel peptide synthesis platform, providing custom libraries of unbound peptides of 5-20 mer at very competitive prices.
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Document-HPLC: 1994_20060721145615.PDF (PDF)