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*For Non-Clinical Research Use Only*
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Neurokinin B  |
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| Full Name |
Neurokinin B |
| Alias |
NKB |
|
Sequence
(one-letter code) |
DMHDFFVGLM-NH2 |
Sequence
(three-letter code) |
{ASP}{MET}{HIS}{ASP}{PHE}{PHE}{VAL}{GLY}{LEU}{MET}-NH2 |
| C-Terminal |
NH2 |
| Description |
Neurokinin B belongs to the tachykinin family. Neurokinin B may play an important role in the olfactory, gustatory, visceral, and neuroendocrine processing information. Neurokinin B is potent bronchioconstrictor and has neruomodulatory roles in various brain functions. Neurokinin B is a member of the tachykinin family of neuropeptides that also includes Substance P and Neurokinin A. These carboxyl terminal-amidated peptides are derived from two preprotachykinin genes - the PPT-A gene encodes the sequences of Substance P, Neurokinin A, and neuropeptide K and the PPT-B gene encodes the sequence of Neurokinin B. Neurokinin B stimulate the production of immunoglobulins in peripheral B lymphocytes, This conditional response to Neurokinin B is likely due NK-3 receptors present only following co-culture and activation. |
| Solubility |
Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents. |
| Purity |
> 95% |
| Storage |
Store at -20°C. |
| Notes |
Novel mammalian Tachykinin in Porcine spinal cord. |
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Document-HPLC: 2033_20060721145617.PDF (PDF)