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*For Non-Clinical Research Use Only*
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N-Acetyl-Asp-Glu  |
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| Full Name |
N-Acetyl-Asp-Glu |
| Alias |
N-Acetylaspartylglutamate NAAG |
|
Sequence
(one-letter code) |
DE |
Sequence
(three-letter code) |
AC-{ASP}{GLU} |
| Description |
Ac-Asp-Glu (N-Acetylaspartylglutamate, NAAG) is an endogeneous peptide with high affinity for a brain Glutamate receptor. Also Ac-Asp-Glu is the most abundant peptide neurotransmitter in the mammalian central nervous system. One role for Ac-Asp-Glu following synaptic release is the activation of metabotropic autoreceptors that inhibit subsequent transmitter release. A second role is the production of extracellular glutamate following Ac-Asp-Glu hydrolysis. High concentrations of Ac-Asp-Glu selectively activate NMDA receptors on mouse spinal cord neurons in cell culture.
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| Solubility |
Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents. |
| Purity |
> 95% |
| Storage |
Before using, store the peptide in the DRY form at 0 - 5°C. For best and repeatable results, rehydrate the peptide immediately before using. Do not re-freeze any unused portions. |
| N-Terminal |
AC |
| Notes |
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1 |
Peptide Services: GenScript's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.
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2 |
Standard Peptide Synthesis: GenScript offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. GenScript FlexPeptideTM technology can synthesize peptide as long as 200 amino acids, a world record for such technology.
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3 |
Peptide Modifications: GenScript offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.
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4 |
Peptide Libraries: GenScript has developed a rapid high-throughput parallel peptide synthesis platform, providing custom libraries of unbound peptides of 5-20 mer at very competitive prices.
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Document-MSDS: 6029_20080924032815.PDF (PDF)