N-Acetyl-Ser-Asp-Lys-Pro

*This product has been discontinued!*

Acetyl Ser-Asp-Lys-Pro is formed in bone marrow cells by enzymatic processing of thymosin β4. It inhibits the entry of pluripotent hemopoietic stem cells into S-phase of the cell cycle and protects against Ara-C lethality in mice. Acetyl Ser-Asp-Lys-Pro is also a specific substrate for the N-terminal active site of angiotensin-converting enzyme, which is responsible for its degradation in vivo.

Cat. No.	RP10555
Size	Buy in bulk

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Overview Properties

Overview

Synonyms	AcSDKP; Ac-S-D-K-P
Description	Acetyl Ser-Asp-Lys-Pro is formed in bone marrow cells by enzymatic processing of thymosin β4. It inhibits the entry of pluripotent hemopoietic stem cells into S-phase of the cell cycle and protects against Ara-C lethality in mice. Acetyl Ser-Asp-Lys-Pro is also a specific substrate for the N-terminal active site of angiotensin-converting enzyme, which is responsible for its degradation in vivo.
Cas No	127103-11-1
Sequence	{SER}{ASP}{LYS}{PRO}
Sequence Shortening	SDKP
Molecular Formula	C₂₀H₃₃N₅O₉
N Terminal	AC
Molecular Weight	487.5

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Properties

Purity	> 95%
Form	Lyophilized
Storage	Store at -20°C.
Note	(CFU-S = Spleen Colony-Forming Units) N-Acetyl-Ser-Asp-Lys-Pro exerts a high inhibitory activity on the proliferation of hematopoietic pluripotent stem cells

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