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Cat. No.
Name
Size   
Price
Selected
RP10623-1
Thrombin Receptor Agonist
1 mg
$62
RP10623-5
Thrombin Receptor Agonist
5 mg
$247
Thrombin Receptor Agonist

Full Name Thrombin Receptor Agonist
Sequence
(one-letter code)
SFLLRNPNDKYEPF
Documents
Document-HPLC: 2054_20060721145618.PDF (PDF)
Document-MS: 1807_20060721145558.PDF (PDF)
Document-MSDS: 5478_20080821233606.PDF (PDF)
TECHNICAL MANUAL: 12464_20100407015038.PDF (PDF)
Figures
Reference
Sequence
(three-letter code)
{SER}{PHE}{LEU}{LEU}{ARG}{ASN}{PRO}{ASN}{ASP}{LYS}{TYR}{GLU}{PRO}{PHE}
Description
A synthetic thrombin receptor agonist peptide (TRP) of 7 residues (SFLLRNP) was found to be as effective as thrombin for Ca2+ mobilization, and both agonists induced Ca2+ release exclusively from internal stores. Thrombin stimulated tyrosine phosphorylation of several proteins of molecular mass 40,000 Da, 42,000 Da, 70,000 Da, 120,000 Da and 130,000 Da. There was a good correlation between thrombin-induced tyrosine phosphorylation of the latter three proteins and Ca2+ mobilization.
Purity
> 95%
Storage
Store at -20°C.
Notes
1
Peptide Services: GenScript's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.
2
Standard Peptide Synthesis: GenScript offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. GenScript FlexPeptideTM technology can synthesize peptide as long as 200 amino acids, a world record for such technology.
3
Peptide Modifications: GenScript offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.
4
Peptide Libraries: GenScript has developed a rapid high-throughput parallel peptide synthesis platform, providing custom libraries of unbound peptides of 5-20 mer at very competitive prices.
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