||αMSH; a-MSH; aMSH; alpha-MSH; alphaMSH;α-Melanocyte Stimulating Hormone; αMelanocyte Stimulating Hormone; a-Melanocyte Stimulating Hormone; aMelanocyte Stimulating Hormone; alpha-Melanocyte Stimulating Hormone; alphaMelanocyte Stimulating Hormone; NDP-MSH[Nle4, D-Phe7]-α-MSH, amide
||[Nle4, DPhe7]-alpha-MSH (NDP-MSH), a highly potent analogue of alpha-melanocyte-stimulating hormone (alpha-MSH), possesses nanomolar efficacies at all the melanocortin receptor subtypes except the MC2R. Evaluation of the melanocortin 'message' sequence of [Nle4, DPhe7]-alpha-MSH was performed on the human melanocortin receptor subtypes designated hMC1, hMC3R, hMC4R, and hMC5R.
|Sequence (one-letter code)
|Sequence (three-letter code)
||Store at -20°C. Keep tightly closed. Store in a cool dry place.
||[Nle4,DPhe7] alpha-MSH is a hormone that stimulates melanogenesis and facilitates learning and memory. [Nle4,DPhe7] alpha-MSH can affect inflammatory and immune responses and peripheral nerve regeneration.
Cragnolini AB, et al. Anxiety-like behavior induced by IL-1beta is modulated by alpha-MSH through central melanocortin-4 receptors. Peptides. Jun 2006; 27(6): 1451-1456.
Yamaoka-Tojo M, et al. Central neurotranspeptide, alpha-melanocyte-stimulating hormone (alpha-MSH) is upregulated in patients with congestive heart failure. Intern. Med. Jul 2006; 45(7): 429-434.