Catalog Products » Other Products » New Products » [Nle4, D-Phe7]-α-Melanocyte Stimulating Hormone (MSH), amide
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Product Name
Size
Price
Quantity
RP10658-1 [Nle4, D-Phe7]-α-Melanocyte Stimulating Hormone (MSH), amide
1 mg
$66.00
[Nle4, D-Phe7]-α-Melanocyte Stimulating Hormone (MSH), Amide

Full Name [Nle4, D-Phe7]-α-Melanocyte Stimulating Hormone (MSH), Amide
Alias
αMSH; a-MSH; aMSH; alpha-MSH; alphaMSH;α-Melanocyte Stimulating Hormone; αMelanocyte Stimulating Hormone; a-Melanocyte Stimulating Hormone; aMelanocyte Stimulating Hormone; alpha-Melanocyte Stimulating Hormone; alphaMelanocyte Stimulating Hormone; NDP-MSH[Nle4, D-Phe7]-α-MSH, amide
Documents
[Nle<sup>4</sup>, D-Phe<sup>7</sup>]-α-Melanocyte Stimulating Hormone (MSH), amideDocument-HPLC: 5273_20080805043453.PDF (PDF)
[Nle<sup>4</sup>, D-Phe<sup>7</sup>]-α-Melanocyte Stimulating Hormone (MSH), amideDocument-MS: 5274_20080805043915.PDF (PDF)
[Nle<sup>4</sup>, D-Phe<sup>7</sup>]-α-Melanocyte Stimulating Hormone (MSH), amideDocument-MSDS: 5428_20080821020004.PDF (PDF)
[Nle<sup>4</sup>, D-Phe<sup>7</sup>]-α-Melanocyte Stimulating Hormone (MSH), amideTECHNICAL MANUAL: Guidelines_for_Dissolving_Peptides.pdf (pdf)
Alias
αMSH; a-MSH; aMSH; alpha-MSH; alphaMSH;α-Melanocyte Stimulating Hormone; αMelanocyte Stimulating Hormone; a-Melanocyte Stimulating Hormone; aMelanocyte Stimulating Hormone; alpha-Melanocyte Stimulating Hormone; alphaMelanocyte Stimulating Hormone; NDP-MSH[Nle4, D-Phe7]-α-MSH, amide
Sequence
(one-letter code)
Ac-SYSNleEHfRWGKPV-NH2
Sequence
(three-letter code)
Ac-{SER}{TYR}{SER}{NLE}{GLU}{HIS}{d-PHE}{ARG}{TRP}{GLY}{LYS}{PRO}{VAL}-NH2
C-Terminal
NH2
Description
[Nle4, DPhe7]-alpha-MSH (NDP-MSH), a highly potent analogue of alpha-melanocyte-stimulating hormone (alpha-MSH), possesses nanomolar efficacies at all the melanocortin receptor subtypes except the MC2R. Evaluation of the melanocortin 'message' sequence of [Nle4, DPhe7]-alpha-MSH was performed on the human melanocortin receptor subtypes designated hMC1, hMC3R, hMC4R, and hMC5R.
MW
1647.000
Formula
C78H111N21O19
Purity
> 95%
Storage
Store at -20°C. Keep tightly closed. Store in a cool dry place.
N-Terminal
Ac
Notes
[Nle4,DPhe7] alpha-MSH is a hormone that stimulates melanogenesis and facilitates learning and memory. [Nle4,DPhe7] alpha-MSH can affect inflammatory and immune responses and peripheral nerve regeneration.
Document-COA
Citation
Cragnolini AB, et al. Anxiety-like behavior induced by IL-1beta is modulated by alpha-MSH through central melanocortin-4 receptors. Peptides. Jun 2006; 27(6): 1451-1456.

Yamaoka-Tojo M, et al. Central neurotranspeptide, alpha-melanocyte-stimulating hormone (alpha-MSH) is upregulated in patients with congestive heart failure. Intern. Med. Jul 2006; 45(7): 429-434.

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1
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