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Cat. No.
Name
Size   
Price
Selected
RP10804-0.5
Galantide
0.500 mg
$71
Galantide

Full Name Galantide
Sequence
(one-letter code)
GWTLNSAGYLLGPQQFFGLM-NH2
Documents
Document-MSDS: 4648_20080630212733.PDF (PDF)
TECHNICAL MANUAL: 12464_20100407015038.PDF (PDF)
Figures
Reference
Sequence
(three-letter code)
{GLY}{TRP}{THR}{LEU}{ASN}{SER}{ALA}{GLY}{TYR}{LEU}{LEU}{GLY}{PRO}{GLN}{GLN}{PHE}{PHE}{GLY}{LEU}{MET}
C-Terminal
NH2
Description
The galanin-antagonist galantide, a chimeric peptide obtained from amino acids 1-13 of galanin attached to the C-terminal fragment of bradykinin, has been found to improve social memory in 'social recognition' test when i.c.v. administered at doses varying from 6-6000nmoles. Galantide causes widespread antagonism to the action of galanin and reversibly blocks the neuronal actions of galanin in a dose-dependent manner. It inhibits the release of acetylcholine, reduces the response to galanin in the hypothalamus, and blocks the effect of galanin on glucose-induced insulin secretion.
Solubility
Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents.
Purity
> 95%
Storage
store at -20°C. Keep tightly closed. Store in a cool dry place.
Notes
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1
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