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*For Non-Clinical Research Use Only*
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Endomorphin-1  |
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| Full Name |
Endomorphin-1 |
| Alias |
Endomorphin1; EM-1; EM1 |
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Sequence
(one-letter code) |
YPWF-NH2 |
Sequence
(three-letter code) |
{TYR}{PRO}{TRP}{PHE}-NH2 |
| C-Terminal |
NH2 |
| Description |
Endomorphin-1 (EM-1) is a recently isolated endogenous peptide having potent analgesic activity and high affinity and selectivity for the mu-opioid receptor. Endomorphin-1 activates G proteins and inhibits adenylyl cyclase activity in membrane preparations from cells stably expressing the mu opioid receptor, an effect reversed by the mu receptor antagonist CTAP (D-Phe-Cys-Tyr-D-Trp-Arg-Thr-Pen-Thr-NH2). However, endomorphin-1 appears to have no influence on cells stably expressing the delta opioid receptor.
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| Solubility |
The peptide is soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weigh out a smaller portion of the contents. |
| Purity |
> 95% |
| Storage |
Store the peptide at -20°C. Keep container tightly closed. |
| Notes |
Endomorphin-1 is a potent, selective endogenous μ opioid receptor agonist. |
Related Products
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1 |
Peptide Services: GenScript's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.
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2 |
Standard Peptide Synthesis: GenScript offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. GenScript FlexPeptideTM technology can synthesize peptide as long as 200 amino acids, a world record for such technology.
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3 |
Peptide Modifications: GenScript offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.
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4 |
Peptide Libraries: GenScript has developed a rapid high-throughput parallel peptide synthesis platform, providing custom libraries of unbound peptides of 5-20 mer at very competitive prices.
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Document-HPLC: 2092_20060721145620.PDF (PDF)
