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*For Non-Clinical Research Use Only*
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Calcitonin, Chicken  |
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| Full Name |
Calcitonin, Chicken |
Sequence
(one-letter code) |
CASLSTCVLGKLSQELHKLQTYPRTDVGAGTP-NH2 |
|
Sequence
(three-letter code) |
{CYS}{ALA}{SER}{LEU}{SER}{THR}{CYS}{VAL}{LEU}{GLY}{LYS}{LEU}{SER}{GLN}{GLU}{LEU}{HIS}{LYS}{LEU}{GLN}{THR}{TYR}{PRO}{ARG}{THR}{ASP}{VAL}{GLY}{ALA}{GLY}{THR}{PRO}-NH2 |
| C-Terminal |
NH2 |
| Chemical Bridge |
Disulfide bridge: Cys1-7 |
| Description |
Calcitonin is a hormone known to participate in calcium and phosphorus metabolism. Calcitonin contains a single disulfide bond, which causes the amino terminus to assume the shape of a ring. Alternative splicing of the calcitonin pre-mRNA can yield a mRNA encoding calcitonin gene-related peptide; that peptide appears to function in the nervous and vascular systems. The calcitonin receptor has been cloned and shown to be a member of the seven-transmembrane, G protein-coupled receptor family.
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| Solubility |
Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents. |
| Purity |
> 95% |
| Storage |
Store at -20°C. |
| Notes |
Calcitonin (chicken), which is a single chain peptide with 32 amino acids, stimulates bone formation by inhibiting osteoblasts. Calcitonin induces bone resorption and increases cAMP levels in osteoclasts. |
Related Products
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1 |
Peptide Services: GenScript's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.
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2 |
Standard Peptide Synthesis: GenScript offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. GenScript FlexPeptideTM technology can synthesize peptide as long as 200 amino acids, a world record for such technology.
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Peptide Modifications: GenScript offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.
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4 |
Peptide Libraries: GenScript has developed a rapid high-throughput parallel peptide synthesis platform, providing custom libraries of unbound peptides of 5-20 mer at very competitive prices.
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Document-HPLC: 2101_20060721145620.PDF (PDF)