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Cat. No.
Name
Size   
Price
Selected
RP11228-0.5
Dermaseptin
0.500 mg
$157
Dermaseptin

Full Name Dermaseptin
Sequence
(one-letter code)
ALWKTMLKKLGTMALHAGKAALGAAADTISQGTQ
Documents
Document-MSDS: 4694_20080702214540.PDF (PDF)
TECHNICAL MANUAL: 12464_20100407015038.PDF (PDF)
Figures
Reference
Sequence
(three-letter code)
{ALA}{LEU}{TRP}{LYS}{THR}{MET}{LEU}{LYS} {LYS}{LEU}{GLY}{THR}{MET}{ALA}{LEU}{HIS} {ALA}{GLY}{LYS}{ALA}{ALA}{LEU}{GLY}{ALA} {ALA}{ALA}{ASP}{THR}{ILE}{SER}{GLN}{GLY} {THR}{GLN}
Description
Dermaseptins are antimicrobial peptides, strings of amino acids, or proteins, of various sizes and shapes. Dermaseptins were isolated from frog skin. Dermaseptin is a crucial part of the frog's immune system, inhibiting the growth of bacteria, protozoa and fungi. Dermaseptins are cationic (positively charged) and 27-34 residues in length. Dermaseptins adopt a largely K-helical conformation when binding to membranes. Like other antimicrobial peptides, dermaseptin is membrane-perturbing; however, unlike other antimicrobial peptides, dermaseptin rests on the surface of the bacterial membrane and does not insert.
Purity
> 95%
Storage
Store at -20°C. Keep tightly closed. Store in a cool dry place.
Notes
Highly potent antimicrobial activity against pathogenic fungi.
1
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4
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