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Hot Products
*For Non-Clinical Research Use Only*
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Hepatitis C Virus NS3 Protease Inhibitor 1  |
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| Full Name |
Hepatitis C Virus NS3 Protease Inhibitor 1 |
| Alias |
HCV NS3 Protease Inhibitor 1 |
|
Sequence
(one-letter code) |
Ac-DEMEEC |
Sequence
(three-letter code) |
{ASP}{GLU}{MET}{GLU}{GLU}{CYS} |
| Description |
Hepatitis Virus C NS3 Protease Inhibitor 1 is a potent peptide inhibitor of hepatitis virus C NS3 protease. The hepatitis C virus (HCV) NS3 protease is essential for polyprotein maturation and viral propagation, and it has been proposed as a suitable target for antiviral drug discovery. An N-terminal hexapeptide cleavage product of a dodecapeptide substrate identified as a weak competitive inhibitor of the NS3 protease activity was optimized to a potent and highly specific inhibitor of the enzyme. The effect of this potent NS3 protease inhibitor was evaluated on replication of subgenomic HCV RNA and compared with interferon- (IFN-), which is currently used in the treatment of HCV-infected patients. |
| Purity |
> 95% |
| Storage |
Store the peptide at -20°C. |
| N-Terminal |
AC |
| Notes |
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Related Products
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1 |
Peptide Services: GenScript's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.
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2 |
Standard Peptide Synthesis: GenScript offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. GenScript FlexPeptideTM technology can synthesize peptide as long as 200 amino acids, a world record for such technology.
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3 |
Peptide Modifications: GenScript offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.
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4 |
Peptide Libraries: GenScript has developed a rapid high-throughput parallel peptide synthesis platform, providing custom libraries of unbound peptides of 5-20 mer at very competitive prices.
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Document-MSDS: 5880_20080919024136.PDF (PDF)