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*For Non-Clinical Research Use Only*
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TAT  |
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| Full Name |
TAT |
Sequence
(one-letter code) |
YGRKKRRQRRR-NH2 |
|
Sequence
(three-letter code) |
{TYR}{GLY}{ARG}{LYS}{LYS}{ARG}{ARG}{GLN}{ARG}{ARG}{ARG}-NH2 |
| C-Terminal |
NH2 |
| Description |
TaT is a transcriptional transactivator protein that binds to a regulatory element in the HIV-1 long terminal repeat. By recruiting P-TEFb to TAR, TaT promotes transcription of viral mRNA. This arginine-rich TAT peptide penetrates plasma membrane directly, but not through endocytosis. TaT has similar immunosuppressive effects as transforming growth factor-beta (TGF beta) and both inhibit lymphocyte proliferation. |
| Purity |
> 95% |
| Storage |
Store at -20°C. Keep tightly closed. Store in a cool dry place. |
| Notes |
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Related Products
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1 |
Peptide Services: GenScript's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.
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2 |
Standard Peptide Synthesis: GenScript offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. GenScript FlexPeptideTM technology can synthesize peptide as long as 200 amino acids, a world record for such technology.
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3 |
Peptide Modifications: GenScript offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.
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4 |
Peptide Libraries: GenScript has developed a rapid high-throughput parallel peptide synthesis platform, providing custom libraries of unbound peptides of 5-20 mer at very competitive prices.
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Document-HPLC: 2159_20060721145623.PDF (PDF)
