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Cat. No.
Name
Size   
Price
Selected
RP12784-0.5
TAT
0.500 mg
$43
RP12784-5
TAT
5 mg
$285
TAT

Full Name TAT
Sequence
(one-letter code)
YGRKKRRQRRR-NH2
Documents
Document-HPLC: 2159_20060721145623.PDF (PDF)
Document-MS: 1912_20060721145603.PDF (PDF)
Document-MSDS: 4310_20080331023958.PDF (PDF)
TECHNICAL MANUAL: 12464_20100407015038.PDF (PDF)
Figures
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Reference
Sequence
(three-letter code)
{TYR}{GLY}{ARG}{LYS}{LYS}{ARG}{ARG}{GLN}{ARG}{ARG}{ARG}-NH2
C-Terminal
NH2
Description
TaT is a transcriptional transactivator protein that binds to a regulatory element in the HIV-1 long terminal repeat. By recruiting P-TEFb to TAR, TaT promotes transcription of viral mRNA. This arginine-rich TAT peptide penetrates plasma membrane directly, but not through endocytosis. TaT has similar immunosuppressive effects as transforming growth factor-beta (TGF beta) and both inhibit lymphocyte proliferation.
Purity
> 95%
Storage
Store at -20°C. Keep tightly closed. Store in a cool dry place.
Notes
Related Products
Cat. No.
Name
Size   
Price
Selected
RP10131-0.5
TAT 2-4
0.500 mg
$81
1
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