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Cat. No.
Name
Size   
Price
Selected
RP13118
N-Cbz-Pro-D-Leu
10 mg
$25
N-Cbz-Pro-D-Leu

Full Name N-Cbz-Pro-D-Leu
Sequence
(one-letter code)
CBZ-PL
Documents
Document-HPLC: 788_20050919140132.PDF (PDF)
Document-MASS_SPECE: 820_20050919140154.PDF (PDF)
Document-MSDS: 5426_20080820233010.PDF (PDF)
TECHNICAL MANUAL: 12464_20100407015038.PDF (PDF)
Figures
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Reference
Sequence
(three-letter code)
CBZ-{PRO}{d-LEU}
Description
The peptide CBZ-Pro-D-Leu, injected daily in mice receiving morphine chronically, is found to prevent development of physical dependence as measured by changes in body temperature and body weight due either to abrupt or to naloxone-induced withdrawal. But the peptide treatment did not alter the acute effects of a challenge dose of morphine on either analgesia or body temperature.
Purity
> 95%
Storage
Store at -20°C. Keep tightly closed. Store in a cool dry place.
N-Terminal
CBZ
Notes
Effective in blocking development of tolerance to actions of morphine on pain threshold body temperature and weight.
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