|
A
B
C
D
E
F
G
H
I
J
K
L
M
N
O
P
Q
R
S
T
U
V
W
X
Y
Z
Hot Products
*For Non-Clinical Research Use Only*
|
Epithelial Membrane Protein (EMP)-1  |
|
|
| Full Name |
Epithelial Membrane Protein (EMP)-1 |
| Alias |
EMP1; epithelial membrane protein-1; epithelial membrane protein |
|
Sequence
(one-letter code) |
GGTYSCHFGPLTWVCKPQGG |
Sequence
(three-letter code) |
{GLY}{GLY}{THR}{TYR}{SER}{CYS}{HIS}{PHE}{GLY}{PRO}{LEU}{THR}{TRP}{VAL}{CYS}{LYS}{PRO}{GLN}{GLY}{GLY} |
| Chemical Bridge |
Disulfide bond: Cys6-Cys15 |
| Description |
EMP-1 is identified as a surface biomarker whose expression correlates with acquisition of gefitinib resistance. EMP-1 expression is further correlated with lack of complete or partial response to gefitinib in lung cancer patient samples as well as clinical progression to secondary gefitinib resistance. EMP-1 expression and acquisition of gefitinib clinical resistance is independent of gefitinib-sensitizing EGFR somatic mutations. |
| Solubility |
Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents. |
| Purity |
> 95% |
| Storage |
Before using, store the peptide in the DRY form at 0 - 5°C. For best and repeatable results, rehydrate the peptide immediately before using. Do not re-freeze any unused portions. |
| Notes |
|
 |
1 |
Peptide Services: GenScript's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.
|
2 |
Standard Peptide Synthesis: GenScript offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. GenScript FlexPeptideTM technology can synthesize peptide as long as 200 amino acids, a world record for such technology.
|
3 |
Peptide Modifications: GenScript offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.
|
4 |
Peptide Libraries: GenScript has developed a rapid high-throughput parallel peptide synthesis platform, providing custom libraries of unbound peptides of 5-20 mer at very competitive prices.
|
|
Document-MSDS: 5434_20080821023846.PDF (PDF)