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*For Non-Clinical Research Use Only*
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SHU 9119  |
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| Full Name |
SHU 9119 |
Sequence (three-letter code) |
Ac-Nle-cyclo[Asp-His-D-Nal(2')-Arg-Trp-Lys]-NH2 |
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| C-Terminal |
Amidation |
| Chemical Bridge |
Asp2-Lys7 |
| Description |
The efficacy and specificity of SHU-9119 as an MC3/MC4 receptor antagonist in the rat was first validated in vitro and in vivo. In vitro, in heterologous cells expressing either rat MC3-R or MC4-R, the major MCR subtypes expressed in brain, SHU-9119 showed no intrinsic agonism. |
| Solubility |
Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents. |
| Purity |
> 95% |
| Storage |
Storage at -20°C. Keep tightly closed. |
| N-Terminal |
Acetylation |
| Notes |
Antagonist of rat MC3 and mouse MC4 receptors. |
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