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*For Non-Clinical Research Use Only*
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[Des-Asp 1]-Angiotensin I, Human  |
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| Full Name |
[Des-Asp1]-Angiotensin I, Human |
| Alias |
Ang I; AngiotensinI; Angiotensin 1; Angiotensin1 |
|
Sequence
(one-letter code) |
RVYIHPFHL |
Sequence
(three-letter code) |
{ARG}{VAL}{TYR}{ILE}{HIS}{PRO}{PHE}{HIS}{LEU} |
| Description |
The renin-angiotensin system plays an important role in regulating blood volume, arterial pressure, cardiac and vascular function, and may contribute to the pathogenesis of atherosclerosis. It stimulates an increase in nitric oxide synthase mRNA, protein expression, and nitric oxide production in pulmonary vessels. This system is found in various vertebrates, from elasmobranchs to mammals. Angiotensins consist of at least three polypeptide hormones: angiotensin I (Ang I), angiotensin II (Ang II), and angiotensin III (Ang III). Ang I is derived from a protein secreted by the liver by the action of renin, angiotensin, which then undergoes proteolytic cleavage to form the decapeptide Ang I. Ang I is converted to Ang II by the angiotensin converting enzyme (ACE) or kininase II, a dipeptidyl-carboxypeptidase. |
| Solubility |
Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents. |
| Purity |
> 95% |
| Storage |
Storage at -20°C. Keep tightly closed. |
| Notes |
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Related Products
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1 |
Peptide Services: GenScript's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.
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2 |
Standard Peptide Synthesis: GenScript offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. GenScript FlexPeptideTM technology can synthesize peptide as long as 200 amino acids, a world record for such technology.
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3 |
Peptide Modifications: GenScript offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.
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4 |
Peptide Libraries: GenScript has developed a rapid high-throughput parallel peptide synthesis platform, providing custom libraries of unbound peptides of 5-20 mer at very competitive prices.
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Document-HPLC: 772_20050919140132.PDF (PDF)