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Cat. No.
Name
Size   
Price
Selected
RP13720
[Sar1, Ile8]-Angiotensin II
5 mg
$38
[Sar1, Ile8]-Angiotensin II

Full Name [Sar1, Ile8]-Angiotensin II
Alias
AngiotensinII; Angiotensin 2; Angiotensin2
Documents
Document-HPLC: 2188_20060721145625.PDF (PDF)
Document-MS: 1941_20060721145604.PDF (PDF)
Document-MSDS: 5699_20080911232804.PDF (PDF)
TECHNICAL MANUAL: 12464_20100407015038.PDF (PDF)
Figures
Reference
Sequence
(one-letter code)
Sar-RVYIHPI
Sequence
(three-letter code)
{SAR}{ARG}{VAL}{TYR}{ILE}{HIS}{PRO}{ILE}
Description
The biological activities of angiotensin II antagonists upon basal and angiotensin II-stimulated aldosterone production were evaluated in an isolated canine glomerulosa cell preparation. Our investigations found that the most potent competitive antagonist of angiotensin II-stimulated aldosterone production was the [Sar1, Ile8] derivative of angiotensin II. However, this peptide was also a partial agonist at concentrations required to inhibit the steroidogenic effect of angiotensin II on dog adrenal cells, and never reduced aldosterone production to basal levels.
Solubility
GenScript angiotensin II is soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weigh out a smaller portion of the contents.
Purity
> 95%
Storage
Storage at -20°C. Keep tightly closed.
Notes
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