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Cat. No.
Name
Size   
Price
Selected
RP17307
Enfuvirtide (T-20)
1 mg
$165
Enfuvirtide (T-20)

Full Name Enfuvirtide (T-20)
Alias
ENF
Documents
Document-MSDS: 5725_20080915212928.PDF (PDF)
TECHNICAL MANUAL: 12464_20100407015038.PDF (PDF)
Figures
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Reference
Sequence
(one-letter code)
Ac-YTSLIHSLIEESQNQQEKNEQELLELDKWASLWNWF-NH2
Sequence
(three-letter code)
Ac-{TYR}{THR}{SER}{LEU}{ILE}{HIS}{SER}{LEU}{ILE}{GLU}{GLU}{SER}{GLN}{ASN}{GLN}{GLN}{GLU}{LYS}{ASN}{GLU}{GLN}{GLU}{LEU}{LEU}{GLU}{LEU}{ASP}{LYS}{TRP}{ALA}{SER}{LEU}{TRP}{ASN}{TRP}{PHE}-NH2
C-Terminal
NH2
Description
36 residue synthetic peptide that inhibits HIV-1 fusion with CD4 cells. N-terminal acetylated, C-terminal amide. Enfuvirtide is the first in this class to reach market approval. Fusion inhibitors block the last step in the three-step viral entry process consisting of attachment, co-receptor binding and fusion, thereby preventing viral capsid entry into the host cell. Enfuvirtide has a unique mechanism of action and high viral target specificity, and in clinical trials has been shown to exhibit both high efficacy and low toxicity. Enfuvirtide is a peptide mimetic of an essential region within viral envelope glycoprotein gp41 that functions by blocking gp41 structural rearrangements at a transitional pre-fusion conformation.
Purity
> 95%
Storage
Store at -20°C. Keep tightly closed. Store in a cool dry place.
N-Terminal
Ac
Notes
1
Peptide Services: GenScript's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.
2
Standard Peptide Synthesis: GenScript offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. GenScript FlexPeptideTM technology can synthesize peptide as long as 200 amino acids, a world record for such technology.
3
Peptide Modifications: GenScript offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.
4
Peptide Libraries: GenScript has developed a rapid high-throughput parallel peptide synthesis platform, providing custom libraries of unbound peptides of 5-20 mer at very competitive prices.
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