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Hot Products
*For Non-Clinical Research Use Only*
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γ-3-Melanocyte-Stimulating Hormone (MSH)  |
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| Full Name |
γ-3-Melanocyte-Stimulating Hormone (MSH) |
| Alias |
γ3-MSH; g-3-MSH; g3MSH; gamma-3-MSH; gamma3-MSHγ-Melanocyte Stimulating Hormone; γ3-Melanocyte Stimulating Hormone; g-3-Melanocyte Stimulating Hormone; g3Melanocyte Stimulating Hormone; gamma-3-Melanocyte Stimulating Hormone; gamma3-Melanocyte Stimulating Hormone |
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Sequence
(one-letter code) |
YVMGHFRWDRFGRRNGSSSSGVGGAAQ |
Sequence
(three-letter code) |
{TYR}{VAL}{MET}{GLY}{HIS}{PHE}{ARG}{TRP}{ASP}{ARG}{PHE}{GLY}{ARG}{ARG}{ASN}{GLY}{SER}{SER}{SER}{SER}{GLY}{VAL}{GLY}{GLY}{ALA}{ALA}{GLN} |
| Description |
Melanocortin (MC) 3-MSH (Melanocyte-Stimulating Hormone) is believed to signal through the MC 3 receptor. It induces a sustained increase in intracellular free calcium levels ([Ca2+]i) in a subpopulation of pituitary cells. Most of the cells responding to 3-MSH express more than one pituitary hormone mRNA. The effect of 3-MSH is blocked by SHU9119, a MC3R and MC4R antagonist, in only 50% of the responsive cells, suggesting that in half of these cells the mediating receptor is not the MC3R. Low picomolar doses of 3-MSH increase [Ca2+]i in the growth hormone (GH)- and prolactin (PRL)-secreting GH3 cell line. |
| Solubility |
Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents. |
| Purity |
> 95% |
| Storage |
Store the peptide at -20°C. Keep container tightly closed. Store in a cool dry place. |
| Notes |
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Related Products
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1 |
Peptide Services: GenScript's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.
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2 |
Standard Peptide Synthesis: GenScript offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. GenScript FlexPeptideTM technology can synthesize peptide as long as 200 amino acids, a world record for such technology.
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3 |
Peptide Modifications: GenScript offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.
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4 |
Peptide Libraries: GenScript has developed a rapid high-throughput parallel peptide synthesis platform, providing custom libraries of unbound peptides of 5-20 mer at very competitive prices.
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Document-MSDS: 5868_20080918211938.PDF (PDF)