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Hot Products
*For Non-Clinical Research Use Only*
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FYQLALT  |
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| Full Name |
FYQLALT |
Sequence
(one-letter code) |
FYQLALT |
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Sequence
(three-letter code) |
H-Phe-Tyr-Gln-Leu-Ala-Leu-Thr-OH
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| Description |
NIVRKKK is a weaker stimulator of the Hsc70 (Heat-shock cognate protein 70) ATPase activity compared with pigeon cytochrome C peptide and FYQLALT, a peptide optimized for binding to Hsc70. FYQLALT effectively blocks the binding of NIVRKKK to Hsc70, possibly by causing a conformational change that masked Hsc70's binding site for the basic
peptide. Two hypotheses are offered to explain the two different peptide motifs. First, it is proposed that Hsc70 recognizes two different amino acid sequence motifs in its dual roles of chaperoning proteins to organelles (NIVRKKK-like sequences) and facilitating protein folding
(FYQLALT-like sequences). Second, the NIVRKKK motif may be used to bind certain folded proteins with which Hsc70 interacts, such as itself, p53, and Dnaj2.
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| Purity |
95% |
| Storage |
Store GenScript FYQLALT at -20°C. |
| Notes |
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1 |
Peptide Services: GenScript's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.
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2 |
Standard Peptide Synthesis: GenScript offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. GenScript FlexPeptideTM technology can synthesize peptide as long as 200 amino acids, a world record for such technology.
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3 |
Peptide Modifications: GenScript offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.
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4 |
Peptide Libraries: GenScript has developed a rapid high-throughput parallel peptide synthesis platform, providing custom libraries of unbound peptides of 5-20 mer at very competitive prices.
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Document-MSDS: 5822_20080917221016.PDF (PDF)