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Hot Products
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Colivelin  |
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| Full Name |
Colivelin |
| Alias |
Colivelin |
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Sequence
(one-letter code) |
SALLRSIPAPAGASRLLLLTGEIDLP |
Sequence
(three-letter code) |
{Ser}{Ala}{Leu}{Leu}{Arg}{Ser}{Ile}{Pro}{Ala}{Pro}{Ala}{Gly}{Ala}{Ser}{Arg}{Leu}{Leu}{Leu}{Leu}{Thr}{Gly}{Glu}{Ile}{Asp}{Leu}{Pro} |
| Description |
Colivelin is a hybrid peptide synthesized to enhance the neuroprotective effects of humanin (HN). Colivelin is constructed as activity-dependent neurotrophic factor (ADNF) C-terminally fused to AGA-(C8R) HNG17, which is a potent HN derivative. Cell death induced by overexpressed familial Alzheimer's disease (FAD)-causative genes and beta-amyloid (1-43) can be completely suppressed by colivelin. Colivelin administered intraperitoneally suppresses memory impairment and may serve as a novel drug candidate to treat Alzheimer's disease. |
| Formula |
C119H206N32O35 |
| M.W. |
2645.1 |
| Storage |
Store at -20°C. Keep tightly closed. Store in a cool dry place. |
*For Non-Clinical Research Use Only*
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Peptide Services: GenScript's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.
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Standard Peptide Synthesis: GenScript offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. GenScript FlexPeptideTM technology can synthesize peptide as long as 200 amino acids, a world record for such technology.
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Peptide Modifications: GenScript offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.
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Peptide Libraries: GenScript has developed a rapid high-throughput parallel peptide synthesis platform, providing custom libraries of unbound peptides of 5-20 mer at very competitive prices.
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MS: 20090316221219 (PDF)