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*For Non-Clinical Research Use Only*
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HABP52  |
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| Full Name |
HABP52 |
Sequence
(one-letter code) |
GAHWQFNALTVRGGGS |
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Sequence
(three-letter code) |
{Gly}{Ala}{His}{Trp}{Gln}{Phe}{Asn}{Ala}{Leu}{Thr}{Val}{Arg}{Gly}{Gly}{Gly}{Ser} |
| Description |
Pep-1 (HABP52 in this paper) isolated by phage display has been shown to bind to hyaluronic acid (HA) with high affinity and to inhibit leukocyte adhesion to HA. This peptide lacks similarity to the HA binding motifs discussed above, in that 2 of 16 amino acids are basic. In contrast, HABP35 possesses 11 of 27 basic residues, which may help contribute to ionic binding of this peptide to negatively charged HA. Pep-1/HABP52 inhibits contact hypersensitivity responses in mice by blocking skin-directed trafficking of inflammatory leukocytes. |
| Purity |
> 95% |
| Notes |
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 |
1 |
Peptide Services: GenScript's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.
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2 |
Standard Peptide Synthesis: GenScript offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. GenScript FlexPeptideTM technology can synthesize peptide as long as 200 amino acids, a world record for such technology.
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3 |
Peptide Modifications: GenScript offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.
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4 |
Peptide Libraries: GenScript has developed a rapid high-throughput parallel peptide synthesis platform, providing custom libraries of unbound peptides of 5-20 mer at very competitive prices.
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Document-MSDS: 9150_20090105230229.PDF (PDF)