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Hot Products
*For Non-Clinical Research Use Only*
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Livin7, ML-IAP  |
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| Full Name |
Livin7, ML-IAP |
Sequence
(one-letter code) |
KWFPSCQFLL |
|
Sequence
(three-letter code) |
{Lys}{Trp}{Phe}{Pro}{Ser}{Cys}{Gln}{Phe}{Leu}{Leu}} |
| Description |
Livin, also known as melanoma inhibitor of apoptosis protein (ML-IAP) is one of recently identified inhibitors of apoptosis protein (IAP) family, which is overexpressed in melanoma cells, rendering them resistant to apoptotic signals. Targeting ML-IAP is a promising approach to treating melanoma. Livin7 peptide has the highest affinity to HLA-A24. Livin/ML-IAP interacts with downstream caspases, such as caspase-3, caspase-7, and caspase-9, leading to their inactivation and degradation.
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| Purity |
> 95% |
| Storage |
Store at -20°C. Keep tightly closed. Store in a cool dry place. |
| Notes |
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1 |
Peptide Services: GenScript's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.
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2 |
Standard Peptide Synthesis: GenScript offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. GenScript FlexPeptideTM technology can synthesize peptide as long as 200 amino acids, a world record for such technology.
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3 |
Peptide Modifications: GenScript offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.
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4 |
Peptide Libraries: GenScript has developed a rapid high-throughput parallel peptide synthesis platform, providing custom libraries of unbound peptides of 5-20 mer at very competitive prices.
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Document-MSDS: 11567_20091214022738.PDF (PDF)