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HIF-1 alpha (556-574)

*This product has been discontinued!*
This is a hypoxia-inducible factor-1 19-mer fragment. HIF-1 functions as master regulator of response to oxygen homeostasis. Hypoxia-induced gene expression is initiated when HIF-1subunit is stabilized in response to a lack of oxygen. This part of HIF-1 binds to the von Hippel-Lindau factor (VHL) an E3 ubiquitin ligase, and the proline 564 is absolutely vital to the binding process.
RP20479
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Overview
Synonyms HIF-1 alpha (556-574)
Description This is a hypoxia-inducible factor-1 19-mer fragment. HIF-1 functions as master regulator of response to oxygen homeostasis. Hypoxia-induced gene expression is initiated when HIF-1subunit is stabilized in response to a lack of oxygen. This part of HIF-1 binds to the von Hippel-Lindau factor (VHL) an E3 ubiquitin ligase, and the proline 564 is absolutely vital to the binding process.
Sequence
{Asp}{Leu}{Asp}{Leu}{Glu}{Met}{Leu}{Ala}{Pro}{Tyr}{Ile}{Pro}
{Met}{Asp}{Asp}{Asp}{Phe}{Gln}{Leu}
Sequence Shortening DLDLEMLAPYIPMDDDFQL
Molecular Formula C101H152N20O34S2
Molecular Weight 2254.6
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Properties
Purity > 95%
Form Lyophilized
Storage Store the peptide at -20°C.
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