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Protein L Resin

Description:

Protein L is an immunoglobulin-binding protein that binds to immunoglobulin kappa light chains without interfering with the antigen-binding site. It binds to a wider range of Ig classes and subclasses than other antibody-binding proteins such as protein A and protein G. Protein L binds to all classes of Ig (IgG, IgM, IgA, IgE and IgD). Protein L also binds to single-chain variable fragments (Scfv) and Fab fragments.
Protein L Resin is made by covalently coupling purified protein L to an agarose support. This leak-resistant coupling method ensures excellent gel stability and binding characteristics.

Total Volume:

5 ml of 50% slurry

Key Features:

• Broad Ig binding spectrum
• High capacity of more than 15 mg immunoglobulin per ml of resin
• Cross-linked agarose media

Characteristics:

Ligand	Purified protein L
Number of Ig binding sites per ligand	5
MW of ligand	Approximately 42 KD
PI of ligand	4.57
Degree of substitution	Approximately 2 mg protein L/ml
Static binding capacity	>15 mg Porcine Ig/ml drained medium
Stability	37°C, 7 days
Matrix spherical	Agarose, 4% cross-linked
Average particle size	90 μm (45–165 μm)
Sanitization	Washing of the packed column with 70% ethanol
Storage	20% ethanol at +4 to +8 °C

Order:

Cat.No. Name Size Price Quantity   L00239 Protein L Resin  2.5 ml $ 145.00

Technical Manual: Download PDF file TM0222 EXAMPLE: Zoom COA:  L00239_R311904  (PDF) MSDS:  20090909220137  (PDF) COA:  L00239_R301911  (PDF) COA:  L00239_R30011003  (PDF)

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