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ToxinEraser^TM Endotoxin Removal Resin

Description:

Lipopolysaccharide (LPS) is a bacterial endotoxin and a major constituent of the cell walls of gram-negative bacteria. During gram-negative bacteremia or endotoxemia, LPS is the principal pathophysiological mediator by which bacteria can cause hypotension, organ failure, disseminated intravascular coagulation, or fatal shock in mammalian hosts. The removal of these endotoxins is highly necessary for downstream processes.
The ToxinEraser^TM Endotoxin Removal Resin utilizes immobilized polymixin B to bind and remove pyrogens from solution. The polymixins are a family of antibiotics that contain a cationic cyclopeptide with a fatty acid chain. Polymixin B neutralizes the biological activity of endotoxins by binding to the lipid A portion of bacterial lipopolysaccharide.

Total Volume:

2 ml of 50% slurry

Key Features:

Superior Stability: This product has both high stability and high removal efficiency.
Excellent Binding Capacity: ToxinEraser^TM has a binding capacity of over 2,000,000 EU/ml (CV).
Strong Resilience: This product may be reused up to five times if properly regenerated.

Order:

Technical Manual:

Download PDF file TM0366

Code	Name	Size	Price
M01053	Buffer: ToxinEraser^TM Regeneration Buffer	125 ml	$ 25.00
M01054	Buffer: ToxinEraser^TM Equilibration Buffer	125 ml	$ 25.00
L00338	ToxinEraser^TM Endotoxin Removal Kit	1 kit	$ 110.00


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