| Catalog No. |
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| Full Name | |
| Alias | Anti TGF-β; Anti TGFβ; Anti TGF-b; Anti TGFb; Anti TGF-beta |
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| Abbreviated Name-2 | Anti Transforming Growth Factor-β; Anti Transforming Growth Factorβ; Transforming Growth Factor-b; Transforming Growth Factorb; Transforming Growth Factor-Beta; Transforming Growth Factorbet |
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| Description | Transforming growth factor-beta (TGF-beta) family of proteins has potent hematopoietic regulatory properties ranging from effects on the growth and differentiation of primitive stem cells to the differentiated functions of mature cells. Although most reports have described the inhibitory activities of TGF-beta on hematopoiesis, recent evidence supports the concept that TGF-beta can have both inhibitory and stimulatory actions on these systems. These differences depend on the differentiation state of the target cell and the other cytokines interacting with the cell. Furthermore, TGF-beta has direct bidirectional effects on cell surface expression of many cytokine receptors suggesting that it is part of the mechanism of action of TGF-beta. The major biological effect of TGF-beta on hematopoietic cell growth is the reversible inhibition of entry into the cell cycle. Importantly, the effect of in vivo administration of TGF-beta has mimicked the in vitro effects. |
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| Ig Subclass | Mouse IgG2b |
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| Storage | The lyophilized product may be stored at 4 °C.
After reconstitution, store any aliquots not intended for use within one month at -20°C. |
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| Stability | The antibody will remain stable for two years in lyophilized form or for one month in solution if stored at 4°C. |
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| Concentration | 1 mg/ml in PBS (after reconstitution) |
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| Clone | A00028.01 |
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| Immunogen | r.HumanEGF |
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| Reconstitution | Reconstitute with sterile H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. |
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| Applications | ELISA and Western blot analysis |
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| Conjugation | Unconjugated |
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| Host Species | Mouse |
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| Antigen Species | Human |
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| Note | Briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container's cap because small volumes of antibody will occasionally become entrapped in the seal of the product vial during shipment and storage. |
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