| Catalog No. |
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| Full Name | |
| Alias | Eotaxin-1; Eotaxin1; Mouse Anti Human Eotaxin-1; Mouse Anti Human Eotaxin1 |
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| Abbreviated Name-2 | mAHuEotaxin-1; mAHuEotaxin1 |
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| Description | Chemokine (C-C motif) ligand 11 (CCL11) is a small cytokine belonging to the CC chemokine family that is also known as eotaxin. CCL11 selectively recruits eosinophilsby inducing their chemotaxis, and therefore, is implicated in allergic responses. The effects of CCL11 are mediated by its binding to a G-protein-linked receptor known as a chemokine receptor. Chemokine receptors for which CCL11 is a ligand include CCR2°CCR3, and CCR5. The gene for human CCL11 (scya11) is encoded on three exons and is located on chromosome 17. |
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| Ig Subclass | Mouse IgG1 |
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| Storage | In lyophilized form, for long periods, store at 4°C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20°C. |
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| Stability | Two years lyophilized, one month in solution at 4°C |
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| Concentration | 1 mg/ml in PBS (after reconstitution) |
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| Clone | A00029.01 |
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| Immunogen | r.human Eotaxin-1 |
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| Purification Method | Ion exchange |
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| Reconstitution | Reconstitute with sterile H2O. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. |
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| Titer | By direct ELISA, 1:10,000 dilution will yield 0.15 OD using alkaline phosphatase conjugated Rabbit Anti-Mouse Ig (Jackson Laboratories). |
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| Applications | ELISA
Western blot
Immuneprecipitation |
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| Conjugation | Unconjugated |
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| Host Species | Mouse |
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| Antigen Species | Human |
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| Note | Briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container's cap because small volumes of antibody will occasionally become entrapped in the seal of the product vial during shipment and storage. |
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