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Mouse Anti-Human IL-1 Beta Monoclonal Antibody  |
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Note: | This product has been discontinued!
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| Full Name | | | Alias | Interleukin-1 β; Interleukin-β; Interleukin-1 b; Interleukin-1b; Interleukin-1 beta; Interleukin-1beta |
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| Abbreviated Name-2 | mAHuIL-1 β; ImAHuIL-β; ImAHuIL-1 b; mAHuIL-1b; mAHuIL-1 beta; mAHuIL-1beta |
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| Description | Interleukin 1 (IL1), originally known as lymphocyte activating factor (LAF), activates T cells and lymphocytes, which then proliferate and secrete interleukin 2. IL1 is primarily released from stimulated macrophages and monocytes, but also from several other cell types. It is thought to play a key role in inflammatory and immune responses. These two closely related agents, interleukin1 alpha (IL1 alpha) and interleukin1 beta (IL1 beta), bind to the same cell surface receptor and elicit nearly identical biological responses. Their amino acid sequences also and share 25% homology. |
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| Ig Subclass | Mouse IgG2b |
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| Storage | The product may be stored for long periods in lyophilized form at 4°C in a dry environment. After reconstitution, aliquot and store any antibody not meant for use within one month at -20°C. |
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| Stability | If stored at 4°C, the product remains stable for two years in lyophilized form or one month in solution. |
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| Concentration | 1 mg/ml in PBS (after reconstitution) |
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| Clone | A00037.01 |
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| Immunogen | rHuman IL-1β |
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| Purification Method | Ion exchange |
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| Reconstitution | Reconstitute with sterile H2O to give a 1 mg/ml concentration. Mix gently, then wash the sides of the vial and wait 30 to 60 seconds before use. |
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| Titer | By direct ELISA, 1:20,000 dilution will yield >1.0 OD using alkaline phosphatase conjugated Rabbit Anti-Mouse Ig (Jackson Laboratories). 1:2,000 dilution will completely inhibit a thymocyte co-stimulation assay using suboptimal doses of concanavalin A. |
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| Applications | ELISA and Western blot analysis |
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| Conjugation | Unconjugated |
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| Host Species | Mouse |
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| Antigen Species | Human |
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| Note | The antibody is produced in BALB/c mice. |
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| * For Non-Clinical Research Use Only *
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Antibody Services: GenScript's custom antibody service guarantees 1:32,000 ELISA titer of final product or two ELISA positive clones with the help of our advanced antigen design tool. |
2 |
Polyclonal
antibody Services: GenScript's custom polyclonal antibody
services start from $250. It comes with a 1:32,000 ELISA titer guarantee, thanks to our advanced
antigen design tool. |
3 |
Custom
Monoclonal Antibody Services: GenScript's custom monoclonal antibody service
guarantees two ELISA positive clones with the help of advanced hybridoma technology & experienced
professional. | |
If you cannot find your antibodies on our list, try our Express AntibodyTM Service, and receive high-quality, titer-guaranteed antibodies in only 5-8 weeks. Our customer service is available 24 hours, Monday through Friday. You may contact us any time for assistance. |
