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Mouse Anti-Human IL-4 Monoclonal Antibody

Note:
This product has been discontinued!

Catalog No. Size Price Figures
Full Name
AliasInterleukin-4; Interleukin4; Mouse Anti Human IL-4; Mouse Anti Human IL4
Abbreviated Name-2mAHuIL-4; mAHuIL4
DescriptionIL4 is a pleiotropic cytokine produced by activated T cells. IL4 is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. IL4, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Ig SubclassMouse IgG2a
StorageIn lyophilized form, for long periods, store at 4°C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20°C.
StabilityTwo years lyophilized, one month in solution at 4°C
Concentration1 mg/ml in PBS (after reconstitution)
CloneA00041.01
Immunogenr.Human IL-4
Purification MethodIon exchange
ReconstitutionReconstitute with sterile H2O. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.
TiterIn direct ELISA, using alkaline phosphatase Goat Anti-Mouse Ig (Jackson Laboratories) 1:10,000 dilution will give 0.3 OD.
ApplicationsELISA
Western blot
Immuneprecipitation
Immunohistochemistry
Intracellular staining
Cross ReactivityNo cross reactivity with murine IL-4 was reported.
ConjugationUnconjugated
Host SpeciesMouse
Antigen SpeciesHuman
NoteBriefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container's cap because small volumes of antibody will occasionally become entrapped in the seal of the product vial during shipment and storage.
* For Non-Clinical Research Use Only *
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