| Catalog No. |
Size |
Price |
Figures |
A00044-100 ug
| 100 ug | $ 50.00 | MSDS: 20051003104713 (PDF)
EXAMPLE:
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References:
- Kurdowska AK, et al. Interleukin-8 and anti-interleukin-8 autoantibodies in gingival crevicular fluid from patients with periodontitis. J. Periodontal. Res. Feb 2003; 38(1): 73-78.
- Mian BM, et al. Fully human anti-interleukin 8 antibody inhibits tumor growth in orthotopic bladder cancer xenografts via down-regulation of matrix metalloproteases and nuclear factor-kappaB. Clin. Cancer Res. Aug 2003; 9(8): 3167-3175.
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A00044-500 ug
| 500 ug | $ 125.00 |
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| Full Name | | Mouse Anti-Human IL-8 Monoclonal Antibody |
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| Alias | Anti IL8; Anti interleukin-8; Anti Interleukin8 |
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| Abbreviated Name-2 | CXCL8 |
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| Description | IL-8, also known as neutrophil chemotactic factor, neutrophil activating protein, and monocyte-derived neutrophil chemotactic factor, is a member of the alpha (C-X-C) subfamily of chemokines called CXCL8. In response to proinflammatory stimuli, IL-8 is produced by monocytes, macrophages, T cells, neutrophils, and fibroblasts. IL-8 promotes neutrophil chemotaxis and degranulation. The 72-amino acid IL-8 is the predominant form secreted by monocytes and lymphocytes. Recombinant human IL-8 is an 8,400 Da protein containing 72 amino acids. The C10 antibody reacts with human Interleukin-8 (IL-8) protein. The immunogen used to produce C10 antibody is recombinant human IL-8 produced in E. coli containing 72 amino acids and having a molecular mass of 8,452 Da. |
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| Ig Subclass | Mouse IgG1 |
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| Storage | The antibody will remain stable for one year from the date of shipment if stored at –20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. Aliquots will remain stable for three months if stored at 4°C. |
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| Concentration | 1 mg/ml in PBS, pH 7.4 with 0.02% sodium azide |
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| Clone | A00044.01 |
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| Immunogen | Purified recombinant human IL-8 |
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| Purification Method | Protein G affinity column |
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| Titer | By direct ELISA, 1:2,000 dilution will yield >1.0 OD using HRP conjugated Goat Anti-Mouse Ig (Calbiochem). |
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| Applications | Working concentrations for specific applications should be determined by the investigator. Appropriate concentrations will be affected by several
factors, including secondary antibody affinity, antigen concentration,
sensitivity of detection method, temperature, and length of incubations,
etc. The suitability of this antibody for applications other than those
listed below has not been determined. The following concentration ranges
are recommended starting points for this product.
ELISA: 0.1-1 ug/ml
Western blot: 1 ug/ml |
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| Fusion Partner | Spleen cells are fused with SP2/0-Ag14 mose myeloma cells. |
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| Conjugation | Unconjugated |
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| Host Species | Mouse |
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| Antigen Species | Human |
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| Note | This antibody is produced in BALB/c mice. |
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