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IL-8 Antibody, mAb, Mouse

Catalog No. Size Price Figures
A00044-100 ug
100 ug
$ 50.00
MSDS:  20051003104713  (PDF)
MSDS:  20080118034804  (PDF)

EXAMPLE:
Mouse Anti Human IL-8 Western Blot
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References:
  • Kurdowska AK, et al. Interleukin-8 and anti-interleukin-8 autoantibodies in gingival crevicular fluid from patients with periodontitis. J. Periodontal. Res. Feb 2003; 38(1): 73-78.
  • Mian BM, et al. Fully human anti-interleukin 8 antibody inhibits tumor growth in orthotopic bladder cancer xenografts via down-regulation of matrix metalloproteases and nuclear factor-kappaB. Clin. Cancer Res. Aug 2003; 9(8): 3167-3175.
A00044-500 ug
500 ug
$ 125.00
Full Name
IL-8 Antibody, mAb, Mouse
Aliashuman IL-8; human Interleukin-8; Interleukin-8
Abbreviated Name-2Neutrophil activating protein-1
DescriptionIL-8, also known as neutrophil chemotactic factor, neutrophil activating protein, and monocyte-derived neutrophil chemotactic factor, is a member of the alpha (C-X-C) subfamily of chemokines called CXCL8. In response to proinflammatory stimuli, IL-8 is produced by monocytes, macrophages, T cells, neutrophils, and fibroblasts. IL-8 promotes neutrophil chemotaxis and degranulation. The 72-amino acid IL-8 is the predominant form secreted by monocytes and lymphocytes. Recombinant human IL-8 is an 8,400 Da protein containing 72 amino acids. This antibody reacts with human Interleukin-8 (IL-8) protein. The immunogen used to produce the antibody is recombinant human IL-8 produced in E. coli containing 72 amino acids and having a molecular mass of 8,452 Da.
Ig SubclassMouse IgG1
StorageThe antibody is stable for 2-3 weeks if stored at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.
Concentration1 mg/ml in PBS, pH 7.4 with 0.02% sodium azide
Clone3B1C10
ImmunogenPurified recombinant human IL-8
Purification MethodProtein G affinity column
ApplicationsWorking concentrations for specific applications should be determined by the investigator. Appropriate concentrations will be affected by several factors, including secondary antibody affinity, antigen concentration, sensitivity of detection method, temperature, and length of incubations, etc. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
ELISA: 0.1-1 µg/ml
Western blot: 1 µg/ml
Fusion PartnerSpleen cells are fused with SP2/0-Ag14 mose myeloma cells.
ConjugationUnconjugated
Host SpeciesMouse
Antigen SpeciesHuman
NoteThis antibody is produced in BALB/c mice.
Technical ManualTM0589TM0590TM0591TM0592TM0593
* For Non-Clinical Research Use Only *
Related Products:
CodeNameSizePrice 
A00044antibody : IL-8 Antibody, mAb, Mouse100 ug
$ 50.00
500 ug
$ 125.00




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