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Mouse Anti-Human Macrophage Inflammatory-1 α Monoclonal Antibody  |
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Note: | This product has been discontinued!
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| Full Name | | | Alias | mAHuMIP-1α |
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| Abbreviated Name-2 | Anti Human Macrophage Inflammatory (MIP)-1α; Anti Human Macrophage Inflammatory (MIP)-1 a; Anti Human Macrophage Inflammatory (MIP)-1a; Anti Human Macrophage Inflammatory (MIP)-1 alpha |
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| Description | Macrophage Inflammatory Proteins (MIP) belong to the family of chemotacticcytokinesknown as chemokines. In humans, there are two major forms, MIP-1α and MIP-1β that are now officially named CCL3 and CCL4 respectively. Both are major factors produced by macrophagesafter they are stimulated with bacterialendotoxins. They activate human granulocytes(neutrophils, eosinophilsand basophils) which can lead to acute neutrophilic inflammation. They also induce the synthesis and release of other pro-inflammatory cytokines such as interleukin 1(IL-1), IL-6and TNF-αfrom fibroblastsand macrophages. The genes for CCL3 and CCL4 are both located on human chromosome 17. |
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| Ig Subclass | Mouse IgG1 |
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| Storage | In lyophilized form, for long periods, store at 4°C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20°C. |
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| Stability | Two years lyophilized, one month in solution at 4°C |
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| Concentration | 1 mg/ml in PBS (after reconstitution) |
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| Clone | A00052.01 |
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| Immunogen | r.Human MIP1-α |
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| Purification Method | Ion exchange |
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| Reconstitution | Reconstitute with sterile H2O. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. |
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| Titer | By direct ELISA, 1:20,000 dilution will yield >1.0 O.D using alkaline phosphatase conjugated rabbit anti-mouse Ig (Jackson Laboratories) |
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| Applications | ELISA
Western blot
Immunoprecipitation |
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| Conjugation | Unconjugated |
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| Host Species | Mouse |
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| Antigen Species | Human |
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| Note | Briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container's cap because small volumes of antibody will occasionally become entrapped in the seal of the product vial during shipment and storage. |
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| Technical Manual | TM0589, TM0590, TM0591, TM0592, TM0593 |
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| * For Non-Clinical Research Use Only *
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Antibody Services: GenScript's custom antibody service guarantees 1:32,000 ELISA titer of final product or two ELISA positive clones with the help of our advanced antigen design tool. |
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Polyclonal
antibody Services: GenScript's custom polyclonal antibody
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Custom
Monoclonal Antibody Services: GenScript's custom monoclonal antibody service
guarantees two ELISA positive clones with the help of advanced hybridoma technology & experienced
professional. | |
If you cannot find your antibodies on our list, try our Express AntibodyTM Service, and receive high-quality, titer-guaranteed antibodies in only 5-8 weeks. Our customer service is available 24 hours, Monday through Friday. You may contact us any time for assistance. |
