| |
Mouse Anti-Human Tumor Necrosis Factor-α Monoclonal Antibody  |
|
|
Note: | This product has been discontinued!
|
| Catalog No. |
Size |
Price |
Figures |
| Full Name | | | Alias | Mouse Anti Human Tumor Necrosis Factor(TNF)αmAb |
|---|
| Abbreviated Name-2 | Anti Tumor Necrosis Factor-α |
|---|
| Description | Tumor necrosis factor is a cytokine involved in systemic inflammation and is a member of a group of cytokines that all stimulate the acute phase reaction. TNF is mainly secreted by macrophages.
TNF causes apoptotic cell death, cellular proliferation, differentiation, inflammation, tumorigenesis and viral replication, TNF is also involved in lipid metabolism, and coagulation. TNF's primary role is in the regulation of immune cells.
Dysregulation and, in particular, overproduction of TNF have been implicated in a variety of human diseases-autoimmune diseases, insulin resistance, and cancer. |
|---|
| Ig Subclass | Mouse IgG1 |
|---|
| Storage | In lyophilized form, for long periods, store at 4°C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20°C. |
|---|
| Stability | Two years lyophilized, one month in solution at 4°C. |
|---|
| Concentration | 1 mg/ml in PBS (after reconstitution) |
|---|
| Clone | A00057.01 |
|---|
| Immunogen | r.Human TNF-α |
|---|
| Purification Method | Ion exchange |
|---|
| Reconstitution | Reconstitute with sterile H2O. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. |
|---|
| Titer | In direct ELISA, using alkaline phosphatase Goat Anti-Mouse Ig (Jackson Laboratories) 1:10,000 dilution will yield 0.7 OD within 10 minutes. |
|---|
| Applications | ELISA
Western blot
Immunoprecipitation
Intracellular staining |
|---|
| Conjugation | Unconjugated |
|---|
| Host Species | Mouse |
|---|
| Antigen Species | Human |
|---|
| Note | This antibody will bind very well to protein A in a buffer (PBS) containing high salt concentration (3M NaCl). |
|---|
| Technical Manual | TM0589, TM0590, TM0591, TM0592, TM0593 |
|---|
| * For Non-Clinical Research Use Only *
 |
1 |
Antibody Services: GenScript's custom antibody service guarantees 1:32,000 ELISA titer of final product or two ELISA positive clones with the help of our advanced antigen design tool. |
2 |
Polyclonal
antibody Services: GenScript's custom polyclonal antibody
services start from $250. It comes with a 1:32,000 ELISA titer guarantee, thanks to our advanced
antigen design tool. |
3 |
Custom
Monoclonal Antibody Services: GenScript's custom monoclonal antibody service
guarantees two ELISA positive clones with the help of advanced hybridoma technology & experienced
professional. | |
If you cannot find your antibodies on our list, try our Express AntibodyTM Service, and receive high-quality, titer-guaranteed antibodies in only 5-8 weeks. Our customer service is available 24 hours, Monday through Friday. You may contact us any time for assistance. |
