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Rat Anti-Mouse IL-4 Monoclonal Antibody  |
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Note: | This product has been discontinued!
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| Full Name | | | Alias | rAmuIL-4; rAmuIL4 |
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| Description | IL4 is a pleiotropic cytokine produced by activated T cells. IL4 is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. IL4, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. |
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| Ig Subclass | Rat IgG1 |
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| Storage | In lyophilized form, for long periods, store at 4°C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20°C. |
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| Stability | Two years lyophilized, one month in solution at 4°C |
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| Concentration | 1 mg/ml in PBS (after reconstitution) |
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| Clone | A00074.01 |
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| Immunogen | r.Murine IL-4 |
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| Purification Method | Ion exchange |
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| Reconstitution | Reconstitute with sterile H2O. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. |
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| Titer | By direct ELISA, 1:5,000 dilution will yield 0.4
OD using alkaline phosphatase conjugated Rabbit Anti-Mouse Ig (Jackson Laboratories).
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| Applications | ELISA
Western blot
Immunoprecipitation
Immunohistochemistry
Intracellular staining |
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| Conjugation | Unconjugated |
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| Host Species | Rat |
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| Antigen Species | Mouse |
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| Note | Briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container's cap because small volumes of antibody will occasionally become entrapped in the seal of the product vial during shipment and storage. |
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| * For Non-Clinical Research Use Only * If you cannot find your antibodies on our list, try our Express AntibodyTM Service, and receive high-quality, titer-guaranteed antibodies in only 5-8 weeks. Our customer service is available 24 hours, Monday through Friday. You may contact us any time for assistance. |
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