| Catalog No. |
Size |
Price |
Figures |
A00092-100 ug
| 100 ug | $ 259.00 | MSDS: 20081019220839 (PDF) EXAMPLE:
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| Full Name | | Mouse Anti-MCL1 Monoclonal Antibody |
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| Alias | Mouse Anti MCL1 |
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| Abbreviated Name-2 | Anti MCL1 |
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| Ig Subclass | Mouse monoclonal IgG |
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| Storage | Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. Aliquot will be stale at 4°C for 3 months. |
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| Specificity | Recognize human MCL1 protein, other species not tested |
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| Concentration | 1 mg/ml in PBS, pH 7.4 with 0.05% sodium azide, frozen liquid |
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| Clone | A00092.01 |
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| Immunogen | Recombinant human MCL1 protein |
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| Purification Method | Immunoaffinity purification |
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| Applications | Western blot: 1:1,000
ELISA: 1:2,000-5,000
Mcl-1 is an anti-apoptotic member of Bcl-2 family originally isolated from the ML-1 human myeloid leukemia cell line during phorbol ester-induced differentiation along the monocyte/macrophage pathway. Mcl-1 localizes to the mitochondria, interacts with and antagonizes pro-apoptotic Bcl-2 family members, and inhibits apoptosis by a number of cytotoxic stimuli. |
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| Conjugation | Unconjugated |
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| Species Reactivity | Human |
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| Host Species | Mouse |
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| Antigen Species | Human |
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| Note | Briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container's cap because small volumes of antibody will occasionally become entrapped in the seal of the product vial during shipment and storage. |