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AMPKα1/AMPKα2 Antibody (Ab-174/172), pAb, Rabbit  |
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| Catalog No. |
Size |
Price |
Figures |
A00664-40 ug
| 40 ug | $ 50.00 | MSDS: 20080118034804 (PDF) MSDS: 20081106025716 (PDF) EXAMPLE:
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A00664-200 ug
| 200 ug | $ 225.00 |
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| Full Name | | AMPKα1/AMPKα2 Antibody (Ab-174/172), pAb, Rabbit |
| | Alias | AMPKα1/AMPKα2 Antibody (Ab-174/172), pAb, Rabbit |
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| Description | Responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-COA carboxylase. It also regulates cholesterol synthesis via phosphorylation and inactivation of hormone-sensitive lipase and hydroxymethylglutaryl-COA reductase. Appears to act as a metabolic stress-sensing protein kinase switching off biosynthetic pathways when cellular ATP levels are depleted and when 5AMP rises in response to fuel limitation and/or hypoxia. This is a catalytic subunit. |
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| Ig Subclass | Rabbit IgG |
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| Storage | Store at -20°C/1 year. |
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| Specificity | GenScript AMPKα1/AMPKα2 Antibody (Ab-174/172) detects endogenous levels of total AMPKα1/AMPKα2 protein. |
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| Concentration | 1 mg/ml in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% sodium azide, and 50% glycerol |
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| Immunogen | Synthesized non-phosphopeptide derived from human AMPKα1/AMPKα2 around the phosphorylation site of threonine 174/172 (L-R-TP-S-C). |
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| Purification Method | GenScript Rabbit Anti-AMPKα1/AMPKα2 Antibody (Ab-174/172) Polyclonal Antibody was purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
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| Applications | IHC: 1:50-1:100 WB: 1:500-1:1,000 IF: 1:100-1:200
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| Conjugation | Unconjugated |
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| Species Reactivity | Human, Mouse, Rat |
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| Host Species | Rabbit |
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| Antigen Species | Human |
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| Note | Briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container's cap because small volumes of antibody will occasionally become entrapped in the seal of the product vial during shipment and storage. |
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| Technical Manual | TM0589, TM0590, TM0591, TM0592, TM0593 | | * For Non-Clinical Research Use Only *
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1 |
Antibody Services: GenScript's custom antibody service guarantees 1:32,000 ELISA titer of final product or two ELISA positive clones with the help of our advanced antigen design tool. |
2 |
Polyclonal
antibody Services: GenScript's custom polyclonal antibody
services start from $250. It comes with a 1:32,000 ELISA titer guarantee, thanks to our advanced
antigen design tool. |
3 |
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Monoclonal Antibody Services: GenScript's custom monoclonal antibody service
guarantees two ELISA positive clones with the help of advanced hybridoma technology & experienced
professional. | |
If you cannot find your antibodies on our list, try our Express AntibodyTM Service, and receive high-quality, titer-guaranteed antibodies in only 5-8 weeks. Our customer service is available 24 hours, Monday through Friday. You may contact us any time for assistance. |