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β-Amyloid (1-28)

Cat. No. Size Price Figures
RP10002-0.5 mg
 		0.5 mg
$ 81.00
MSDS:  20080924020714  (PDF)
HPLC:  20090423040518  (PDF)
MS:  20090423041334  (PDF)


References:
  • Park HY, et al. Modulation of neutrophil apoptosis by beta-amyloid proteins. Int. Immunopharmacol. Jul 2006; 6(7): 1061-1069.
  • Song Y, et al. Comparison of MR images and histochemical localization of intra-arterially administered microglia surrounding beta-amyloid deposits in the rat brain. Histol. Histopathol. Jul 2006; 21(7): 705-711.
  • Gorbita CH. The structure of nanotubes formed by diphenylalanine, the core recognition motif of Alzheimer's beta-amyloid polypeptide. Chem. Commun(Camb). Jun 2006; 14(22): 2332-2334.
Full Name
β-Amyloid (1-28)
Alias Abeta 1-28
Sequence
(one-letter code)		 DAEFRHDSGYEVHHQKLVFFAEDVGSNK
Sequence
(three-letter code)		{ASP}{ALA}{GLU}{PHE}{ARG}{HIS}{ASP}{SER}{GLY}{TYR}
{GLU}{VAL}{HIS}{HIS}{GLN}{LYS}{LEU}{VAL}{PHE}{PHE}
{ALA}{GLU}{ASP}{VAL}{GLY}{SER}{ASN}{LYS}
DescriptionBeta amyloid is an extracellular filamentous protein deposit found in the brain. It is the major protein component of amyloid cores and neuritic plaques and is also found as a deposit in neurofibrillary tangles. Beta-amyloid peptide (Abeta), the major constituent of amyloid plaques in the brains of Alzheimer’s patients, is thought to be the cause of Alzheimer’s Disease (AD). Beta-amyloid peptide is generated from the beta-amyloid precursor protein (beta APP) in a two-step process.
SolubilitySoluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents.
FormulaC145H209N41O46
M.W.3262.5
Cas109770-29-8
Purity> 95%
StorageStore at -20°C.
NotesForms fibrils that have the same antigenic and structural features as the native Alzheimer Disease Amyloid filaments.
* For Non-Clinical Research Use Only *
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