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β-Amyloid (25-35)  |
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| Cat. No. |
Size |
Price |
Figures |
RP10008-1 mg
| 1 mg | $ 52.25 | HPLC: 20060721145613 (PDF) MS: 20060721145553 (PDF) MSDS: 20080626015725 (PDF)
References:
- Mantha AK, et al. Neuroprotective role of neurokinin B (NKB) on beta-amyloid (25-35) induced toxicity in aging rat brain synaptosomes: involvement in oxidative stress and excitotoxicity. Biogerontology. Feb 2006; 7(1): 1-17.
- Fang F, Liu GT. Protective effects of compound FLZ on beta-amyloid peptide-(25-35)-induced mouse hippocampal injury and learning and memory impairment. Acta. Pharmacol. Sin. Jun 2006; 27(6): 651-658.
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RP10008-5 mg
| 5 mg | $ 209.00 |
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| Full Name | |
| Alias |
βAmyloid; b-Amyloid; bAmyloid; beta-Amyloid; betaAmyloid |
Sequence (one-letter code) |
GSNKGAIIGLM | Sequence (three-letter code) | {GLY}{SER}{ASN}{LYS}{GLY}{ALA}{ILE}{ILE}{GLY}{LEU} {MET} | | Description | Beta-amyloid protein (Abeta), a major component of senile plaques of Alzheimer's disease (AD) in the brain, causes elevation of the intracellular free Ca2+ level and the production of robust free radicals. Beta-amyloid 25-35 induced apoptosis, characterized by decreased cell viability, neuronal DNA condensation, and fragmentation, is associated with an increase in intracellular free Ca2+ level, the accumulation of reactive oxygen species (ROS), and the activation of caspase-3. All of these effects induced by beta-amyloid 25-35 are reversed by genistein. |
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| Solubility | The peptide is soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents. |
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| Formula | C45H81N13O14S1 | | M.W. | 1060.27 | | Cas | 131602-53-4 |
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| Purity | > 95% | | Storage | Store the peptide at -20°C |
| * For Non-Clinical Research Use Only *
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