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β-Amyloid (25-35)

Cat. No. Size Price Figures
RP10008-1 mg
 		1 mg
$ 52.00
HPLC:  20060721145613  (PDF)
MS:  20060721145553  (PDF)
MSDS:  20080626015725  (PDF)


References:
  • Mantha AK, et al. Neuroprotective role of neurokinin B (NKB) on beta-amyloid (25-35) induced toxicity in aging rat brain synaptosomes: involvement in oxidative stress and excitotoxicity. Biogerontology. Feb 2006; 7(1): 1-17.
  • Fang F, Liu GT. Protective effects of compound FLZ on beta-amyloid peptide-(25-35)-induced mouse hippocampal injury and learning and memory impairment. Acta. Pharmacol. Sin. Jun 2006; 27(6): 651-658.
RP10008-5 mg
 		5 mg
$ 209.00
Full Name
β-Amyloid (25-35)
Alias βAmyloid; b-Amyloid; bAmyloid; beta-Amyloid; betaAmyloid
Sequence
(one-letter code)		 GSNKGAIIGLM
Sequence
(three-letter code)		{GLY}{SER}{ASN}{LYS}{GLY}{ALA}{ILE}{ILE}{GLY}{LEU}
{MET}
DescriptionBeta-amyloid protein (Abeta), a major component of senile plaques of Alzheimer's disease (AD) in the brain, causes elevation of the intracellular free Ca2+ level and the production of robust free radicals. Beta-amyloid 25-35 induced apoptosis, characterized by decreased cell viability, neuronal DNA condensation, and fragmentation, is associated with an increase in intracellular free Ca2+ level, the accumulation of reactive oxygen species (ROS), and the activation of caspase-3. All of these effects induced by beta-amyloid 25-35 are reversed by genistein.
SolubilityThe peptide is soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents.
FormulaC45H81N13O14S1
M.W.1060.27
Cas131602-53-4
Purity> 95%
StorageStore the peptide at -20°C
* For Non-Clinical Research Use Only *
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