Peptide Products
You are here:  Products » Peptide Products » Catalog Peptides - Hot Products »  β-Amyloid (1-42), human   
 
A  B  C  D  E  F  G  H  I  J  K  L  M  N  O  P  Q  R  S  T  U  V  W  X  Y  Z  ALL  HotProducts  
Search by Catalog Number :(eg.RP01001)
Search by Name :(eg.Parathyroid Hormone (PTH))
Search by Sequence : (One letter code)
Search by Sequence : (Three letter code)

 
β-Amyloid (1-42), human

Cat. No. Size Price Figures
RP10017-0.5 mg
 		0.5 mg
$ 118.75
HPLC:  20060721145613  (PDF)
MS:  20060721145553  (PDF)
MSDS:  20080923043843  (PDF)

EXAMPLE:
beta-amyloid( 1-42) Example
Zoom

References:
  • Murphy GM Jr, et al. Development of a monoclonal antibody specific for the COOH-terminal of beta-amyloid 1-42 and its immunohistochemical reactivity in Alzheimer's disease and related disorders. Am J Pathol. May 1994; 144(5): 1082-1088.
  • Ambroggio EE, et al. Surface behavior and lipid interaction of Alzheimer beta-amyloid peptide 1-42: a membrane-disrupting peptide. Biophys J. Apr 2005; 88(4): 2706-2713.
  • Hulstaert F, et al. Improved discrimination of AD patients using beta-amyloid(1-42) and tau levels in CSF. Neurology. May 1999; 52(8): 1555-1562.
Full Name
β-Amyloid (1-42), human
Sequence
(one-letter code)		 DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA
Sequence
(three-letter code)		{ASP}{ALA}{GLU}{PHE}{ARG}{HIS}{ASP}{SER}{GLY}{TYR}
{GLU}{VAL}{HIS}{HIS}{GLN}{LYS}{LEU}{VAL}{PHE}{PHE}
{ALA}{GLU}{ASP}{VAL}{GLY}{SER} {ASN}{LYS}{GLY}{ALA}{ILE}
{ILE}{GLY}{LEU}{MET}{VAL}{GLY}{GLY}{VAL}{VAL}{ILE}
{ALA}
DescriptionThis peptide is well suited to the quantitative determination of A 42 peptide. Alzheimer’s disease (AD) is characterized by the presence of extracellular plaques and intracellular neurofibrillary tangles (NFTs) in the brain. The major protein component of these plaques is beta amyloid peptide (A), a 40- to 43- amino-acid peptide cleaved from amyloid precursor protein by secretase (BACE) and a putative (gamma) secretase. Increased release of the ‘longer forms’ of A peptide, A 42 and A 43, which have a greater tendency to aggregate than A 40, occurs in individuals expressing certain genetic mutations, expressing certain ApoE alleles or may other, still undiscovered factors.
SolubilityInsoluble in water, may be dissolved in any buffer with pH greater than 9
FormulaC203H311N55O60S1
M.W.4514.1
Cas107761-42-2
Purity> 95%
StorageStore at -20°C
NotesPredominant form found in the brains of patients with Alzheimer's Disease and Down's Syndrome
* For Non-Clinical Research Use Only *
Related Products:
CodeNameSizePrice 
RP10002peptide : β-Amyloid (1-28)0.5 mg
$ 80.75
RP10008 peptide : β-Amyloid (25-35)1 mg
$ 52.25
5 mg
$ 209.00
RP10004peptide : β-Amyloid (1-40)0.5 mg
$ 114.00
RP10013 peptide : β-Amyloid (1-42), rat0.5 mg
$ 175.75
RP10016peptide : β-Amyloid (1-40), rat0.5 mg
$ 156.75
RP10034 peptide : β-Amyloid (42-1)0.5 mg
$ 285.00
GN001027ORF Clone : APP10 ug
$ 2820.00
GN029425 ORF Clone : APP10 ug
$ 2891.25
GN029426ORF Clone : APP10 ug
$ 2610.00
GN046871 ORF Clone : APP10 ug
$ 2891.25




Our customer service is available 24 hours a day, Monday through Friday. You may contact us any time for assistance.