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Urotensin I

Cat. No. Size Price Figures
RP10094-0.5 mg
0.5 mg
$ 118.75
HPLC:  20060721145613  (PDF)
MS:  20060721145553  (PDF)
MSDS:  20080624042643  (PDF)


References:
  • Le Mevel JC, et al. Cardiovascular actions of the stress-related neurohormonal peptides, corticotropin-releasing factor and urotensin-I in the trout Oncorhynchus mykiss. Gen. Comp. Endocrinol. Mar 2006; 146(1): 56-61.
  • Craig PM, et al. Differential increase in forebrain and caudal neurosecretory system corticotropin-releasing factor and urotensin I gene expression associated with seawater transfer in rainbow trout. Endocrinology. Sep 2005; 146(9): 3851-3860.
  • Lu W, et al. Coexpression of corticotropin-releasing hormone and urotensin i precursor genes in the caudal neurosecretory system of the euryhaline flounder (Platichthys flesus): a possible shared role in peripheral regulation. Endocrinology. Dec 2004; 145(12): 5786-5797.
Full Name
Urotensin I
Alias U I, UrotensinI; Urotensin 1; Urotensin1
Sequence
(one-letter code)
NDDPPISIDLTFHLLRNMIEMARIENEREQAGLNRKYLDEV
Sequence
(three-letter code)
{ASN}{ASP}{ASP}{PRO}{PRO}{ILE}{SER}{ILE}{ASP}{LEU}
{THR}{PHE}{HIS}{LEU}{LEU}{ARG}{ASN}{MET}{ILE}{GLU}
{MET}{ALA}{ARG}{ILE}{GLU}{ASN}{GLU}{ARG}{GLU}{GLN}
{ALA}{GLY}{LEU}{ASN}{ARG}{LYS}{TYR}{LEU}{ASP}{GLU}
{VAL}
C-TerminalNH2
DescriptionUrotensins are neuropeptide secreted from the urophysis in the caudal neurosecretory system of the fishes. Two bioactive Urotensins, Urotensin I and Urotensin II have been cloned from various species including mammals. Urotensin I is a 41 aa peptide, which showed prolonged hypotensive effects in mammals. Urotensin I is structurally similar to mammalian corticotropin-releasing factor. Urotensin I is found in the brain of most fish species. It may be involved in the regulation of blood pressure in fish. Urotensin I is closely related to mammalian urocortin and releases ACTH from cultured rat pituitary cells.
SolubilitySoluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents.
FormulaC210H340N62O67S2
M.W.4869.45
Cas83930-33-0
Purity> 95%
StorageBefore using, store the peptide in the DRY form at 0-5°C. For best and repeatable results, rehydrate the peptide immediately before using. Do not re-freeze any unused portions.
* For Non-Clinical Research Use Only *
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