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Urocortin II, human

Cat. No. Size Price Figures
RP10098-0.5 mg
 		0.5 mg
$ 166.00
MSDS:  20080924040829  (PDF)


References:
  • Million M, et al. Human urocortin II, a new CRF-related peptide, displays selective CRF(2)-mediated action on gastric transit in rats. Am. J. Physiol. Gastrointest. Liver Physiol. Jan 2002; 282(1): G34-G40.
  • Inoue K, et al. Human urocortin II, a selective agonist for the type 2 corticotropin-releasing factor receptor, decreases feeding and drinking in the rat. J. Pharmacol. Exp. Ther. Apr 2003; 305(1): 385-393.
  • Karteris E, et al. Urocortin II is expressed in human pregnant myometrial cells and regulates myosin light chain phosphorylation: potential role of the type-2 corticotropin-releasing hormone receptor in the control of myometrial contractility. Endocrinology. Feb 2004; 145(2): 890-900.
Full Name
Urocortin II, human
Alias hUcn II; UCN II; UCNII; UCN 2; UCN2, UrocortinII; Urocortin 2; Urocortin2
Sequence
(one-letter code)		 IVLSLDVPIGLLQILLEQARARAAREQATTNARILARVGHC-NH2
Sequence
(three-letter code)		{ILE}{VAL}{LEU}{SER}{LEU}{ASP}{VAL}{PRO}{ILE}{GLY}
{LEU}{LEU}{GLN}{ILE}{LEU}{LEU}{GLU}{GLN}{ALA}{ARG}
{ALA}{ARG}{ALA}{ALA}{ARG}{GLU}{GLN}{ALA}{THR}{THR}
{ASN}{ALA}{ARG}{ILE}{LEU}{ALA}{ARG}{VAL}{GLY}{HIS}
{CYS}-NH2
C-TerminalNH2
DescriptionHuman urocortin (hUcn) II is a new member of the corticotropin-releasing-factor (CRF) family. It selectively binds to the CRF2 receptor. Human urocortin II exhibits mild motor-suppressive effects and delayed anxiolytic-like effects，suggesting a time-dependent role for hUcn II in the regulation of stress-related behavior.
FormulaC194H339N63O54S
M.W.4450.28
Purity> 95%
StorageStore at -20°C
* For Non-Clinical Research Use Only *
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