| Cat. No. |
Size |
Price |
Figures |
|---|
RP10112-5 mg
| 5 mg | $ 23.75 | HPLC: 20060721145613 (PDF)
MS: 20060721145553 (PDF)
MSDS: 20080626053749 (PDF)
STRUCTURE:
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References:
- Kirchberger NM, et al. Effects of TRH on heteromeric rat erg1a/1b K+ channels are dominated by the rerg1b subunit. J. Physiol. Feb 2006; 571(Pt 1): 27-42.
- Pekary AE, et al. Rapid modulation of TRH and TRH-like peptide levels in rat brain and peripheral tissues by corticosterone. Neurochem. Int. Feb 2006; 48(3): 208-217.
- Soysal S, et al. The basal and TRH stimulated levels of prolactin in low risk climacteric patients with increased breast density: A matched pair case control trial. Maturitas. May 2006; 54(2): 103-109.
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| Full Name | | Thyrotropin-Releasing Hormone (TRH) |
|
| Alias |
L-Pyroglutamyl-L-histidyl-L-prolinamide, Thyroliberin |
Sequence
(one-letter code) |
pEHP-NH2 |
Sequence
(three-letter code) | {pGLU}{HIS}{PRO}-NH2 |
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| C-Terminal | NH2 |
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| Description | Thyrotropin-releasing hormone (TRH) is a tripeptide hormone secreted by the hypothalamus that stimulates the release of thyrotropin. This tripeptide is involved in the regulation of the hypothalamic pituitary-thyroid axis; it stimulates the synthesis and release from the anterior pituitary of thyrotropin (TSH) and prolactin. |
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| Solubility | The peptide is soluble in water to 10 mg/ml, appearing clear and colorless. |
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| Formula | C16H22N6O4 |
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| M.W. | 362.38 |
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| Cas | 24305-27-9 |
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| Purity | > 95% |
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| Storage | Store the peptide at -20°C. Keep container tightly closed. |
| Notes | TRH and phorbol esters stimulate sphingomyelin synthesis in GH3 pituitary cells. |
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